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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
FXa
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "FXa" in MCE Product Catalog:
19
Target:
Áreas de investigación:
Rivaroxaban (BAY 59-7939) is a highly potent, selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM) .
10
10 Cited Publications
Synonyms: DU-176
Áreas de investigación:
Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research .
10
10 Cited Publications
Synonyms: DU-176b
Áreas de investigación:
Edoxaban (DU-176b) tosylate is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Kis of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban tosylate exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban tosylate can be used for preventing thromboembolic disease research .
10
10 Cited Publications
Synonyms: DU-176b monohydrate
Áreas de investigación:
Edoxaban (DU-176b) monohydrate is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Kis of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban monohydrate exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban monohydrate can be used for preventing thromboembolic disease research .
5
5 Cited Publications
Synonyms: PRT054021
Target:
Áreas de investigación:
Betrixaban (PRT054021) is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor with an IC50 of 1.5 nM. Betrixaban shows antithrombotic effect .
5
5 Cited Publications
Synonyms: PRT054021 maleate
Target:
Áreas de investigación:
Betrixaban (PRT054021) maleate is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor with an IC50 of 1.5 nM. Betrixaban maleate shows antithrombotic effect .
2
1
1 Cited Publications
Referencia número: HY-P99283
No. CAS: 1312299-39-0
Synonyms: NN 7415; mAb 2021; Anti-TFPI Recombinant Antibody
1
Target:
Áreas de investigación:
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.
1
Target:
Áreas de investigación:
1
1
1 Cited Publications
Referencia número: HY-76948
No. CAS: 865479-71-6
Target:
Áreas de investigación:
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM).
1
Referencia número: HY-W001294
No. CAS: 109431-87-0
Áreas de investigación:
(R)-(-)-N-Boc-3-pyrrolidinol is a chiral pyrrolidine derivative. After undergoing configuration inversion via the Mitsunobu reaction, (R)-(-)-N-Boc-3-pyrrolidinol can serve as a precursor for the (3S)-aryloxypyrrolidine fragment, which is used to construct key intermediates of FXa inhibitors (such as DX-9065a (HY-10722)) and various chiral drugs. (R)-(-)-N-Boc-3-pyrrolidinol can be applied in studies related to arrhythmia .
Referencia número: HY-50903R
No. CAS: 366789-02-8
Synonyms: BAY 59-7939 (Standard)
Target:
Áreas de investigación:
Rivaroxaban (Standard) is the analytical standard of Rivaroxaban. This product is intended for research and analytical applications. Rivaroxaban (BAY 59-7939) is a highly potent, selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM) .
Synonyms: DU-176-d6
Referencia número: HY-75680
No. CAS: 503614-91-3
Target:
Áreas de investigación:
Apixaban ethyl ester is a key intermediate in the synthesis of FXa inhibitors, which is used to study the inhibitory activity against venous thrombosis .
Referencia número: HY-10264R
No. CAS: 480449-70-5
Synonyms: DU-176 (Standard)
Target:
Áreas de investigación:
Edoxaban (Standard) is the analytical standard of Edoxaban. This product is intended for research and analytical applications. Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research .
Áreas de investigación:
Edoxaban impurity 4 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention .
Synonyms: PD-0348292
Target:
Áreas de investigación:
Eribaxaban (PD-0348292) is an orally active and selective FXa inhibitor with a Ki value of 0.32 nM. Eribaxaban reduces thrombus formation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
