452 Results for "

Fungal Inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (452)

452 Results for "Fungal Inhibitor" in MCE Product Catalog:

56
56 Publications Verification
Cat. No.: HY-16589
CAS No.: 579-13-5
Synonyms: MCH 32
Oligomycin A (MCH 32), created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity.
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43
43 Cited Publications
Cat. No.: HY-N0150
CAS No.: 22373-78-0
Synonyms: Monensin A sodium
Monensin (Monensin A) sodium, an orally active antibiotic, is an ionophore that mediates Na +/H + exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .
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43
43 Cited Publications
Cat. No.: HY-N4302
CAS No.: 17090-79-8
Synonyms: Monensin A
Monensin (Monensin A), an orally active antibiotic, is an ionophore that mediates Na +/H + exchange. Monensin is a potent Wnt signaling inhibitor. Monensin causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .
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32
32 Cited Publications
Cat. No.: HY-12686
CAS No.: 253863-19-3
Purity:  99.30%
Synonyms: FR148083; L783279; LL-Z 1640-2
5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively.
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30
30 Cited Publications
Cat. No.: HY-B0105
CAS No.: 65277-42-1
Synonyms: Ketoconazol; R 41400
Research Areas:  

Infection Cancer

Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
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13
13 Cited Publications
Cat. No.: HY-N0889
CAS No.: 481-46-9
Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC50 of 5.92 μΜ .
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12
12 Cited Publications
Cat. No.: HY-N6798
CAS No.: 35891-70-4
Synonyms: Thermozymocidin; ISP-I
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection .
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11
11 Cited Publications
Cat. No.: HY-76200
CAS No.: 137234-62-9
Synonyms: UK-109496
Target:  

Fungal Bacterial

Research Areas:  

Infection Neurological Disease Cancer

Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. Voriconazole can penetrate the blood brain barrier (BBB) .
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11
11 Cited Publications
Cat. No.: HY-17006A
CAS No.: 162808-62-0
Synonyms: MK-0991; L-743872
Research Areas:  

Infection Cancer

Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
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11
11 Cited Publications
Cat. No.: HY-17006
CAS No.: 179463-17-3
Synonyms: MK-0991 diacetate; L-743872 diacetate
Research Areas:  

Infection Cancer

Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
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8
8 Cited Publications
Cat. No.: HY-B0133
CAS No.: 7681-93-8
Synonyms: Pimaricin
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .
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6
6 Cited Publications
Cat. No.: HY-N6735
CAS No.: 183506-66-3
Synonyms: OSI 2040
Apicidin (OSI 2040) is a fungal metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .
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5
5 Cited Publications
Cat. No.: HY-14273
CAS No.: 241479-67-4
Purity:  99.97%
Synonyms: BAL-4815; RO-0094815
Research Areas:  

Infection Cancer

Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
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3
3 Cited Publications
Cat. No.: HY-B0850
CAS No.: 119446-68-3
Research Areas:  

Infection

Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .
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3
3 Cited Publications
Cat. No.: HY-B0848
CAS No.: 41814-78-2
Tricyclazole is a pentaketone melanin biosynthesis inhibitor and a unique fungicide for controlling rice blast. Tricyclazole alters the structure and function of fungal cell walls, reduces fungal pathogenicity and penetration, and causes dose-dependent liver damage in animals .
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2
2 Cited Publications
Cat. No.: HY-76200S
CAS No.: 1217661-14-7
Synonyms: UK-109496-d3
Voriconazole-d3 is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
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2
2 Cited Publications
Cat. No.: HY-N3617
CAS No.: 531-29-3
Synonyms: Laricin
Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal melanization. Coniferin inhibits the release of certain hormones from cells, including Prostaglandin E2 and Thromboxane B2 .
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2
2 Cited Publications
Cat. No.: HY-N6679A
CAS No.: 21178-57-4
10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity .
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2
2 Cited Publications
Cat. No.: HY-17643
CAS No.: 1340593-59-0
Synonyms: VT-1161
Target:  

Fungal Cytochrome P450

Research Areas:  

Infection

Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .
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2
2 Cited Publications
Cat. No.: HY-K1052

MCE Amphotericin B, Sterile (250 μg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Amphotericin B is a polyene antifungal antibiotic produced by Streptomyces nodosus. It can bind with sterols to form transmembrane channels, resulting in the leakage of intracellular substances, thus inhibiting fungal and yeast contamination.

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