Search Result

Results for "

G6PD

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) Autophagy (2) CD47 (1) Endogenous Metabolite (5) IAP (1) Mitochondrial Metabolism (2) Mitophagy (2) NADPH Oxidase (3) Parasite (2) PDI (2) Reference Standards (4) Small Interfering RNA (siRNA) (3) SOD (2)
By Research Areas:	Cancer (11) Cardiovascular Disease (2) Endocrinology (1) Infection (3) Inflammation/Immunology (6) Metabolic Disease (9)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (3)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0120A

Polydatin 10+ Cited Publications Piceid	Autophagy Apoptosis Mitophagy	Inflammation/Immunology Cancer
Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses.

HY-W107464

G6PDi-1 5+ Cited Publications	PDI	Metabolic Disease Inflammation/Immunology
G6PDi-1 is a reversible and non-competitive **glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC₅₀** of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells .

HY-W010342

6-Aminonicotinamide 15+ Cited Publications	NADPH Oxidase	Cancer
6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP ⁺-dependent enzyme **glucose-6-phosphate dehydrogenase (G6PD) inhibitor (K_i**=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells .

HY-123962

G6PD activator AG1 5+ Cited Publications	NADPH Oxidase	Metabolic Disease
G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) agonist with an EC50 of 3 μM. G6PD is an oxidoreductase that catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone and the simultaneous reduction of NAD phosphate (NADP) to reduced NADP (NADPH). G6PD activator AG1 can reduce hemolysis of human erythrocytes .

HY-16438

RRx-001 Maximum Cited Publications 20 Publications Verification Nibrozetone	CD47 Apoptosis Parasite	Infection Inflammation/Immunology Cancer
RRx-001, a hypoxia-selective epigenetic agent and studied as a radio- and chem-sensitizer, triggers apoptosis and overcomes agent resistance in myeloma. RRx-001 exhibits potent anti-tumor activity with minimal toxicity . RRx-001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP-α . RRx-001 is a potent inhibitor of *G6PD* and shows potent antimalarial activity .

HY-125863

Glucose-6-phosphate dehydrogenase, Microorganism G6PD	Endogenous Metabolite	Metabolic Disease Cancer
Glucose-6-phosphate dehydrogenase, Microorganism (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase, Microorganism is a primary source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, cytochrome p450 systems, and others. Glucose-6-phosphate dehydrogenase, Microorganism is applicable in research related to diabetes, endothelial dysfunction, cancer, and cardiomyopathy .

HY-W017960

Diludine Et-HE; 1,4-DHP	SOD	Endocrinology
Diludine (BNP-7787) is an orally effective feed additive. Diludine reduces the activity of *G6PD* and increases the level of superoxide dismutase (SOD). Diludine reduces the mutagenic effect of environmental pollutants, protects parental reproductive systems and improves offspring quality. Diludine is mainly applied during the transition period of dairy cows to increase milk yield and milk fat content, and improve health status during parturition. Diludine can be used in animal feeding research .

HY-W587796

6-Phosphoglucono-δ-lactone 6-PGδL; 6-Phosphonoglucono-D-lactone	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
6-Phosphoglucono-δ-lactone (6-PGδL), a reversal substrate of glucose-6-phosphate dehydrogenase (G6PD), is an intermediate compound in the oxidative branch of the pentose phosphate pathway (PPP). 6-Phosphoglucono-δ-lactone produced from D-glucose-6-phosphate by glucose-6-phosphate dehydrogenase (G6PDH) and is converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone can be used for heart failure, type 2 diabetes and cancers research .

HY-125863C

Glucose-6-phosphate dehydrogenase, Bacillus sp. G6PD, Bacillus sp.	Endogenous Metabolite	Others
Glucose-6-phosphate dehydrogenase, Bacillus sp. catalyzes the conversion of glucose-6-phosphate into 6-phosphogluconolactone, and produces reduced nicotinamide adenine dinucleotide phosphate (NADPH) and ribose-5-phosphate in this process. Glucose-6-phosphate dehydrogenase, Bacillus sp. can be used in research about diabetic complications .

HY-106328

Fluasterone 1 Publications Verification	Mitochondrial Metabolism	Metabolic Disease Inflammation/Immunology Cancer
Fluasterone is a potent *G6PD* inhibitor with a K_i of 0.51 μM. Fluasterone has anti-inflammatory, cancer preventive, and anti-diabetic effects. Fluasterone is orally active .

HY-N0120AR

Polydatin (Standard) 10+ Cited Publications Piceid (Standard)	Reference Standards Autophagy Apoptosis Mitophagy	Inflammation/Immunology Cancer
Polydatin (Standard) is the analytical standard of Polydatin. This product is intended for research and analytical applications. Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses.

HY-125863B

Glucose 6-phosphate dehydrogenase (yeast, recombinant) G6PD (yeast, recombinant)	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Glucose 6-phosphate dehydrogenase (yeast, recombinant) is the rate-limiting enzyme of the pentose phosphate pathway and a major source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems. Glucose 6-phosphate dehydrogenase helps cells resist oxidative stress and regulates metabolic rates. It holds potential for research in fields such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy .

HY-RS05194

G6PD Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
G6PD Human Pre-designed siRNA Set A contains three designed siRNAs for G6PD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

G6PD Human Pre-designed siRNA Set A G6PD Human Pre-designed siRNA Set A

HY-125863A

Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) G6PD (Leuconostoc sp., recombinant)	Endogenous Metabolite	Metabolic Disease
Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) is an NADP-dependent enzyme in the pentose phosphate pathway, which is one of the ways glucose is metabolized. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) can be used to quantify ATP, glucose, and creatine kinase .

HY-RS22997

G6pd Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
G6pd Rat Pre-designed siRNA Set A contains three designed siRNAs for G6pd gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

G6pd Rat Pre-designed siRNA Set A G6pd Rat Pre-designed siRNA Set A

HY-W010342R

6-Aminonicotinamide (Standard)	NADPH Oxidase Reference Standards	Cancer
6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells .

HY-136783

G6PD-IN-2	Parasite	Infection
G6PD-IN-2 is a Plasmodium falciparum glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC₅₀ value of 0.2 μM. G6PD-IN-2 exerts weak inhibitory activity on Plasmodium falciparum **glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho) with an IC₅₀** value of 22.0 μM. G6PD-IN-2 inhibits growth of Plasmodium falciparum 3D7 strain and exhibits low cytotoxicity in hepatocytes. G6PD-IN-2 can be used for the research of malaria .

HY-W017960R

Diludine (Standard) Et-HE (Standard); 1,4-DHP (Standard)	SOD Reference Standards	Metabolic Disease
Diludine (Standard) is the analytical standard of Diludine (HY-W017960). This product is intended for research and analytical applications. Diludine (BNP-7787) is an orally effective feed additive. Diludine reduces the activity of *G6PD* and increases the level of superoxide dismutase (SOD). Diludine reduces the mutagenic effect of environmental pollutants, protects parental reproductive systems and improves offspring quality. Diludine is mainly applied during the transition period of dairy cows to increase milk yield and milk fat content, and improve health status during parturition. Diludine can be used in animal feeding research .

HY-106328R

Fluasterone (Standard)	Mitochondrial Metabolism Reference Standards	Metabolic Disease Inflammation/Immunology Cancer
Fluasterone (Standard) is the analytical standard of Fluasterone. This product is intended for research and analytical applications. Fluasterone is a potent G6PD inhibitor with a Ki of 0.51 μM. Fluasterone has anti-inflammatory, cancer preventive, and anti-diabetic effects. Fluasterone is orally active .

HY-RS15375

UBL4A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
UBL4A Human Pre-designed siRNA Set A contains three designed siRNAs for UBL4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

UBL4A Human Pre-designed siRNA Set A UBL4A Human Pre-designed siRNA Set A

HY-W248922

2,6-Dibromo-4-(hydroxymethyl)phenol	PDI	Infection
2,6-Dibromo-4-(hydroxymethyl) phenol (Compound 5) acts as a selective inhibitor of Saccharomyces cerevisiae glucose-6-phosphate dehydrogenase, with an IC50 value of 50.2 μM, and shows no activity against Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase .

HY-182002

Apoptosis inducer 61	Apoptosis IAP	Cancer
Apoptosis inducer 61 (Compound 4E) is an Apoptosis inducer. Apoptosis inducer 61 significantly downregulates the expression of BIRC3 and activates Apoptosis. Anticancer agent 313 exhibits anticancer activity against ER ⁺ breast cancer cells, triple-negative breast cancer cells, and gastric cancer cells .

Polydatin 10+ Cited Publications Piceid	Structural Classification Classification of Application Fields Anti-aging Polygonaceae Reynoutria japonica Houtt. Plants Stilbenes Phenols Polyphenols Inflammation/Immunology Disease Research Fields Source Classification Cancer	Autophagy Apoptosis Mitophagy
Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses.

Glucose-6-phosphate dehydrogenase, Microorganism G6PD	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Glucose-6-phosphate dehydrogenase, Microorganism (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase, Microorganism is a primary source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, cytochrome p450 systems, and others. Glucose-6-phosphate dehydrogenase, Microorganism is applicable in research related to diabetes, endothelial dysfunction, cancer, and cardiomyopathy .

Polydatin (Standard) 10+ Cited Publications Piceid (Standard)	Structural Classification Stilbenes Classification of Application Fields Anti-aging Polygonaceae Reynoutria japonica Houtt. Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification Cancer	Reference Standards Autophagy Apoptosis Mitophagy
Polydatin (Standard) is the analytical standard of Polydatin. This product is intended for research and analytical applications. Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses.

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70283

	G6PD Protein, Human (HEK293, His) rHuGlucose-6-phosphate 1-dehydrogenase/G6PD, His; Glucose-6-Phosphate 1-Dehydrogenase; G6PD	Human	HEK293
	The G6PD protein is a rate-limiting enzyme in the oxidative pentose phosphate pathway located in the cytosol, which is crucial for the catabolism of carbohydrates in glycolysis. The primary function of G6PD is to provide reducing power in the form of NADPH and generate pentose phosphates, helping the cell resist oxidative stress and regulate metabolic rates. Additionally, the activity of G6PD is associated with cancer progression. The G6PD protein (Human, HEK293, His) is a recombinant G6PD protein expressed in HEK293 cells, with a C-terminal His tag, and consists of 514 amino acids (A2-L515) .

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (5) Rabbit (3)
Reactivity:	Human (8) Rat (4) Mouse (5) Rabbit (2)
Application:	IHC-P (8) ICC/IF (5) IP (2) WB (6) FC (5) ELISA (3)
Isotype:	IgG (3) IgG1 (4)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (3) Monoclonal Antibody (1) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85177

	Glucose 6 Phosphate Dehydrogenase Antibody (YA4869) G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD	WB, IHC-P, ICC/IF, FC, ELISA	Human
	Glucose 6 Phosphate Dehydrogenase Antibody (YA4869) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.

HY-P80688

	Glucose 6 Phosphate Dehydrogenase Antibody (YA411) G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	Glucose 6 Phosphate Dehydrogenase Antibody (YA411) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.

HY-P810629

	Glucose 6 Phosphate Dehydrogenase Antibody (YA9891) G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD	WB, ICC/IF, IHC-P, FC	Human
	Glucose 6 Phosphate Dehydrogenase Antibody (YA9891) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.

HY-P80688A

	Glucose 6 Phosphate Dehydrogenase Antibody (YA411)(PBS only) G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD	WB, IHC-P, IP	Human, Rat
	Glucose 6 Phosphate Dehydrogenase Antibody (YA411) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.

HY-P88719

	UBL4A Antibody (YA8403) DX254E; DXS254E; G6PD; GDX; GET5; MDY2; TMA24; UBL4	IHC-P, ICC/IF	Human, Mouse, Rat
	UBL4A Antibody (YA8403) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBL4A.

HY-P88719A

	UBL4A Antibody (YA8403)(PBS only) DX254E; DXS254E; G6PD; GDX; GET5; MDY2; TMA24; UBL4	IHC-P, ICC/IF	Human, Mouse, Rat
	UBL4A Antibody (YA8403) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBL4A.

HY-P84063

	Glucose 6 Phosphate Dehydrogenase Antibody (YA3760) G6PD1	WB, IHC-P, FC, ELISA	Human, Mouse, Rabbit
	Glucose 6 Phosphate Dehydrogenase Antibody (YA3760) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.

HY-P84063A

	Glucose 6 Phosphate Dehydrogenase Antibody (YA3760)(PBS only) G6PD1	WB, IHC-P, FC, ELISA	Human, Mouse, Rabbit
	Glucose 6 Phosphate Dehydrogenase Antibody (YA3760) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

G6PD Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
G6PD Human Pre-designed siRNA Set A contains three designed siRNAs for G6PD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

G6pd Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
G6pd Rat Pre-designed siRNA Set A contains three designed siRNAs for G6pd gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

UBL4A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
UBL4A Human Pre-designed siRNA Set A contains three designed siRNAs for UBL4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks