1. Search Result
Search Result
Results for "

GDH

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

1

Screening Libraries

1

Biochemical Assay Reagents

4

Natural
Products

4

Recombinant Proteins

2

Isotope-Labeled Compounds

5

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13653
    (-)-Epigallocatechin Gallate
    Maximum Cited Publications
    57 Publications Verification

    EGCG; Epigallocatechol Gallate

    Endogenous Metabolite Apoptosis Inflammation/Immunology Cancer
    (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
    (-)-Epigallocatechin Gallate
  • HY-103096
    R162
    10+ Cited Publications

    Glutamate Dehydrogenase (GLDH) Cancer
    R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties.
    R162
  • HY-163316
    SIRT4-IN-1
    2 Publications Verification

    Sirtuin Glutamate Dehydrogenase (GLDH) PDHK Metabolic Disease Cancer
    SIRT4-IN-1 is a selective and potent Sirtuin 4 (Sirt4) inhibitor with an IC50 of 16 μM for hSirt4. SIRT4-IN-1 also inhibits hSirt1, hSirt2, hSirt3, hSirt4 and hSirt6. SIRT4-IN-1 competes with acyl peptide substrate for Sirt4's acyl binding site, and is noncompetitive with NAD +. SIRT4-IN-1 increases glutamate dehydrogenase (GDH) activity and rescues pyruvate dehydrogenase (PDH) activity. SIRT4-IN-1 inhibits adipocyte differentiation and suppresses Sirt4 overexpression-induced increased differentiation. SIRT4-IN-1 can be used for the researches of cancer and metabolic disease .
    SIRT4-IN-1
  • HY-13653R
    (-)-Epigallocatechin Gallate (Standard)
    Maximum Cited Publications
    57 Publications Verification

    EGCG(Standard); Epigallocatechol Gallate (Standard)

    Reference Standards Endogenous Metabolite Apoptosis Inflammation/Immunology Cancer
    (-)-Epigallocatechin Gallate (Standard) is the analytical standard of (-)-Epigallocatechin Gallate. This product is intended for research and analytical applications. (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
    (-)-Epigallocatechin Gallate (Standard)
  • HY-N4322
    Decursinol angelate
    1 Publications Verification

    PKC Inflammation/Immunology Cancer
    Decursinol angelate acts as a PKC activator and GDH inhibitor, with an IC50 of 1.432 μM against human GDH. Decursinol angelate activates PKC, downregulates PKCα and PKCβII isoforms, and exerts cytotoxic activity against cancer cells. Decursinol angelate binds to GDH and inhibits its enzymatic activity. Decursinol angelate inhibits VEGF-induced autophosphorylation of VEGFR2, downstream p42/44 ERK and JNK-MAPK signaling pathways, as well as the angiogenesis process. Decursinol angelate is applicable to research related to cancer and leukemia .
    Decursinol angelate
  • HY-E70014

    FAD-GDH; Glucose 1-dehydrogenase

    Endogenous Metabolite Others
    FAD-dependent glucose dehydrogenase (EC 1.1.5.9), or glucose dehydrogenase (FAD)/Pseudomonas glucose dehydrogenase. FAD-dependent glucose dehydrogenase is insensitive to O2 and displays high substrate specificity to glucose and thus is especially attractive enzymes for use in glucose biosensor applications .
    FAD-dependent glucose dehydrogenase
  • HY-P3186A

    GDH-NAD

    Endogenous Metabolite Metabolic Disease
    NAD-dependent glucose dehydrogenase (GDH-NAD) is an oxidoreductase that uses NAD + as a coenzyme, specifically catalyzes the dehydrogenation of glucose to gluconolactone, and reduces NAD + to NADH. NAD-dependent glucose dehydrogenase exhibits favorable substrate selectivity and stability, and is not affected by oxygen .
    NAD-dependent Glucose dehydrogenase
  • HY-P3186

    Endogenous Metabolite Metabolic Disease
    Glucose dehydrogenase, recombinant Microorganisms is a FDA-dependent oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP + to NADPH or, to a lesser extent, NAD + to NADH. Glucose dehydrogenase (GDH) accepts both NAD + and NADP + as cofactors and can be used for the regeneration of NADH and NADPH .
    Glucose dehydrogenase, recombinant Microorganisms
  • HY-E70075

    GDH-TIM; GDH-TPI

    Transketolase Metabolic Disease
    α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is an enzyme mixture composed of glycerol phosphate dehydrogenase (GDH) and triphosphate isomerase (TIM). α-Glycerophosphate Dehydrogenase-Triosephosphate can be used to determine the activity of transketolase (TK) in hemolytic substances of red blood cells to evaluate vitamin B deficiency .
    α-Glycerophosphate Dehydrogenase-Triosephosphate
  • HY-150526

    Endogenous Metabolite Apoptosis Inflammation/Immunology Cancer
    EGCG-4″-sulfate is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate sulfate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. EGCG-4″-sulfate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
    EGCG-4″-sulfate
  • HY-13653S1

    EGCG-d4; Epigallocatechol Gallate-d4

    Isotope-Labeled Compounds Apoptosis Inflammation/Immunology Cancer
    (-)-Epigallocatechin Gallate-d4 (EGCG-d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
    (-)-Epigallocatechin Gallate-d4
  • HY-170017S

    EGCG-d3/d4; Epigallocatechol Gallate-d3/d4

    Isotope-Labeled Compounds Apoptosis Inflammation/Immunology Cancer
    (-)-Epigallocatechin Gallate-d3/d4 (EGCG-d3/d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
    (−)-Epigallocatechin Gallate-d3/d4
  • HY-RS03217

    Small Interfering RNA (siRNA) Others

    CRYL1 Human Pre-designed siRNA Set A contains three designed siRNAs for CRYL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CRYL1 Human Pre-designed siRNA Set A
    CRYL1 Human Pre-designed siRNA Set A
  • HY-RS05980

    Small Interfering RNA (siRNA) Others

    H6PD Human Pre-designed siRNA Set A contains three designed siRNAs for H6PD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    H6PD Human Pre-designed siRNA Set A
    H6PD Human Pre-designed siRNA Set A
  • HY-RS05507

    Small Interfering RNA (siRNA) Others

    GLUD1 Human Pre-designed siRNA Set A contains three designed siRNAs for GLUD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GLUD1 Human Pre-designed siRNA Set A
    GLUD1 Human Pre-designed siRNA Set A
  • HY-RS15422

    Small Interfering RNA (siRNA) Others

    UGDH Human Pre-designed siRNA Set A contains three designed siRNAs for UGDH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    UGDH Human Pre-designed siRNA Set A
    UGDH Human Pre-designed siRNA Set A
  • HY-134136

    Endogenous Metabolite Others
    Octanoyl coenzyme A is an enoyl-CoA hydratase binder. Octanoyl coenzyme A binds to the active site of enoyl-CoA hydratase, occupies the binding pocket for the fatty acid tail of the enzyme's substrate, and induces a conformational shift in a flexible protein loop via its longer octanoyl chain, forming an open channel leading to the inter-trimer gap .
    Octanoyl Coenzyme A
  • HY-134136B

    S-Octanoate-CoA triammonium; S-​Octanoate-coenzyme A triammonium

    Biochemical Assay Reagents Others
    Octanoyl coenzyme A triammonium is an enoyl-CoA hydratase binder. Octanoyl coenzyme A triammonium binds to the active site of enoyl-CoA hydratase, occupies the binding pocket for the fatty acid tail of the enzyme's substrate, and induces a conformational shift in a flexible protein loop via its longer octanoyl chain, forming an open channel leading to the inter-trimer gap .
    Octanoyl coenzyme A triammonium
  • HY-103096R

    Glutamate Dehydrogenase (GLDH) Reference Standards Cancer
    R162 (Standard) is the analytical standard of R162 (HY-103096). This product is intended for research and analytical applications. R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties.
    R162 (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: