21 Results for "

Gelsemium

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Gelsemium" in MCE Product Catalog:

Cat. No.: HY-N0388
CAS No.: 509-15-9
Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.
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Cat. No.: HY-N1440
CAS No.: 1358-76-5
Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models .
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Cat. No.: HY-N4031
CAS No.: 82375-29-9
Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
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Cat. No.: HY-N0969
CAS No.: 113973-31-2
Synonyms: 19-(Z)-Akuammidine; (Z)-Rhazine
(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans .
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Cat. No.: HY-N3939
CAS No.: 865187-17-3
Synonyms: 16-epi-Nb-Methylvoacarpine
Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .
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Cat. No.: HY-N3940
CAS No.: 38990-03-3
Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation activity with IC50 values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively .
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Cat. No.: HY-N1020
CAS No.: 122590-03-8
Target:  

Others

Research Areas:  

Others

11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans .
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Cat. No.: HY-N1599
CAS No.: 114027-38-2
Synonyms: 16-epi-Voacarpine
16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .
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Cat. No.: HY-N4030
CAS No.: 82354-38-9
Synonyms: Gelsenicine
Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment .
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Cat. No.: HY-N12576
CAS No.: 1358-75-4
Koumidine is an alkaloid that can be isolated from Gelsemium elegans .
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Cat. No.: HY-N3186
CAS No.: 125180-42-9
N-Methoxyanhydrovobasinediol is an alkaloid that can be isolated from Gelsemium elegans. N-Methoxyanhydrovobasinediol can be used as a reference .
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Cat. No.: HY-117034
CAS No.: 106466-66-4
Rankinidine is an oxindole alkaloid that is isolated from the MeOH extract of the stem of Gelsemium rankinii .
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Cat. No.: HY-N1019
CAS No.: 122590-04-9
Synonyms: N-Methyl-11-hydroxyrankinidine
Target:  

Others

Research Areas:  

Others

11-Hydroxyhumantenine is an alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .
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Cat. No.: HY-N7507A
CAS No.: 17994-15-9
Target:  

Wnt β-catenin

Research Areas:  

Cancer

Sempervirine is an alkaloid derived from Gelsemium elegans Benth.. Sempervirine inhibits the proliferation of hepatocellular carcinoma (HCC) cells and induces apoptosis by regulating Wnt/β-catenin pathway .
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Cat. No.: HY-N7507
CAS No.: 549-92-8
Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively .
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Cat. No.: HY-N4032
CAS No.: 114027-39-3
Humantenidine, an indole alkaloid, is isolated from Gelsemium sempervirens.
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Cat. No.: HY-N7508
CAS No.: 82375-30-2
Humantenirine is an indole alkaloid isolated from Gelsemium sempervirens .
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Cat. No.: HY-N3416
CAS No.: 113900-75-7
Koumine N-oxide is an alkaloid compound isolated from the herb Gelsemium elegans .
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Cat. No.: HY-N1018
CAS No.: 1195760-68-9
Target:  

Others

Research Areas:  

Others

11-Hydroxygelsenicine is a 11-hydroxy-substituted gelsedine-type indole alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .
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Cat. No.: HY-N0388R
CAS No.: 509-15-9
Gelsemine (Standard) is the analytical standard of Gelsemine. This product is intended for research and analytical applications. Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.
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