Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
49 Results for "
H12
" in MedChemExpress (MCE) Product Catalog:
Products (49)
49 Results for "H12" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: R 125489
Target:
Research Areas:
Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively .
1
Target:
Research Areas:
Cat. No.: HY-P990858
Research Areas:
Tepoxalin is an orally active dual inhibitor of Cyclooxygenase/Lipoxygenase, with IC50 values of 4.6 μM (sheep cyclooxygenase), 2.85 μM (rat cyclooxygenase), 0.15 μM (rat 5-lipoxygenase), and 3.0 μM (h12-lipoxygenase), respectively. Tepoxalin inhibits ROS production and NF-κB activation. Tepoxalin suppresses the production of thromboxane B2, leukotriene B4, prostaglandins and cytokines, and blocks platelet aggregation. Tepoxalin exhibits potent anti-inflammatory activity in rats with adjuvant-induced arthritis. Tepoxalin possesses analgesic activity. Tepoxalin shows no ulcerogenic activity within the anti-inflammatory dose range. Tepoxalin can be used in studies related to adjuvant-induced arthritis, skin inflammation and Alzheimer's disease .
Cat. No.: HY-50097
CAS No.: 55289-36-6
Cat. No.: HY-RS05947
Target:
Research Areas:
H1-2 Human Pre-designed siRNA Set A contains three designed siRNAs for H1-2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-153184
CAS No.: 1159408-61-3
Research Areas:
GalNAc-L96 free base is a conjugate of GalNAc and its ligand L96. When conjugated with the A-rich HCV sequence (H12), GalNAc-L96 free base binds potently to ASGPR, with a Ki value of 10.4 nM. GalNAc-L96 free base promotes siRNA delivery to hepatocytes .
Cat. No.: HY-P99620
CAS No.: 1443004-15-6
Synonyms: CT-P22; CT120
Target:
Research Areas:
Cat. No.: HY-P1507
CAS No.: 89105-94-2
Target:
Research Areas:
Cat. No.: HY-175412
CAS No.: 142473-18-5
Synonyms: Dodecylmercapto-S-(poly(tris(hydroxymethyl)acrylamidomethane); H12-TAC
Target:
Research Areas:
DDTAC (H12-TAC) is a detergent that can extract and solubilize membrane proteins. DDTAC has a thio dodecanoyl chain linked to a polar group made of Tris polyalcoholic moieties and can be utilized in extracting yeast ATP synthase from mitochondrial membranes .
Cat. No.: HY-P99131
Target:
Research Areas:
Cat. No.: HY-121366
CAS No.: 58769-20-3
Synonyms: RU-15525
Target:
Research Areas:
Kadethrin is a synthetic pyrethroid that acts as an insecticide. Kadethrin can affect the binding of [3H] full-histamine toxin ([3H]H12-HTX) to the nicotinic acetylcholine (Ach) receptor/channel binding sites, and it inhibits the Ca 2+ flux through the receptor ion channels .
Cat. No.: HY-160162
CAS No.: 1820602-13-8
Target:
Research Areas:
SR 11023 is an orally active antagonist of PPARγ, with the IC50 value of 109 nM that plays an important role in diabetic research .
Cat. No.: HY-W016149
CAS No.: 1192-52-5
Synonyms: Dichloro-1,2-dithiacyclopentenone
Cat. No.: HY-RS15986
Target:
Research Areas:
ZC3H12A Human Pre-designed siRNA Set A contains three designed siRNAs for ZC3H12A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15987
Target:
Research Areas:
ZC3H12D Human Pre-designed siRNA Set A contains three designed siRNAs for ZC3H12D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21269
Target:
Research Areas:
Zc3h12d Mouse Pre-designed siRNA Set A contains three designed siRNAs for Zc3h12d gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
