Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
HIV-1 protease-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "HIV-1 protease-IN-1" in MCE Product Catalog:
Cat. No.: HY-144688
CAS No.: 2765293-30-7
HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie [1].
1
1 Cited Publications
Cat. No.: HY-N10420
CAS No.: 26543-89-5
Category:
Infection Arnica chamissonis Less. Acanthaceae Lignans Phenylpropanoids Plants Disease Research Fields
Target:
Cat. No.: HY-N0556
CAS No.: 219944-39-5
Category:
Infection Aesculus chinensis Bunge Other Terpenoids Hippocastanaceae Terpenoids Plants Disease Research Fields
Target:
Cat. No.: HY-N10420R
CAS No.: 26543-89-5
Synonyms: (-)-HINokININ (Standard)
Target:
Cat. No.: HY-P2054
CAS No.: 125552-93-4
Target:
Research Areas:
Cat. No.: HY-N3502
CAS No.: 852936-69-7
Target:
Cat. No.: HY-N0556R
CAS No.: 219944-39-5
Target:
Cat. No.: HY-139794
CAS No.: 164514-54-9
SDZ283-910 is a potent human immunodeficiency virus type-1 (HIV-1) protease inhibitor .
Cat. No.: HY-124360
CAS No.: 299922-10-4
Target:
Research Areas:
NIT is an inhibitor of HIV-1 protease (HIV-1p) with Ki values of 96 and 91 μM for WT HIV-1p and MDR HIV-1p, respectively [1].
Cat. No.: HY-125148
CAS No.: 178820-70-7
Target:
Research Areas:
AQ148 is a HIV-1 protease inhibitor (Ki=137 nM). The IC50 values ??of AQ148 for the inhibition of HIV-1, HIV-2 and SIV aspartic proteases are 1.5 μM, 3.4 μM and 5 μM, respectively [1].
Cat. No.: HY-17367S
CAS No.: 1092540-56-1
Synonyms: BMS-232632-d15
Cat. No.: HY-17367S1
CAS No.: 1092540-52-7
Synonyms: BMS-232632-d18
Cat. No.: HY-P4466
CAS No.: 130877-92-8
Target:
Research Areas:
Cat. No.: HY-120812
CAS No.: 160729-91-9
Target:
Research Areas:
HIV-IN-11 is part of the hydroxylaminoglutaramide (HAPA) transition state isomeric series of HIV protease inhibitors and is a potent and selective inhibitor of HIV-1 protease. HIV-IN-11 competitively inhibits HIV-1 PR (Ki: 0.049 nM) and potently inhibits replication of HIV(IIIb)-infected MT4 lymphocytes at concentrations of 25.0-50.0 nM. HIV-IN-11 displays a longer half-life than indinavir sulfate in animal models and serves as a promising second-generation HIV protease inhibitor .
Cat. No.: HY-179586
Target:
Research Areas:
HIV-1-IN-91 (Compound BAN) is a HIV-1 protease inhibitor .
Cat. No.: HY-183562
CAS No.: 253265-95-1
Synonyms: UIC-94003
Target:
Research Areas:
TMC-126 (UIC-94003) is a non-peptidic HIV-1 protease (HIV-1 protease) inhibitor. TMC-126 exhibits highly potent antiproliferative activity against wild-type HIV-1. TMC-126 can be used in studies related to HIV infection [1] .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
