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Isoforms Recommended:	HO-2

Results for "

HO-2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Heme Oxygenase (HO) (3) Cytochrome P450 (1) Reactive Oxygen Species (ROS) (3) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (3) Inflammation/Immunology (1) Metabolic Disease (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Heme Oxygenase (HO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147817

Heme Oxygenase-2-IN-1	Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Heme Oxygenase-2-IN-1 (Compound 9) is a potent, selective heme oxygenase-2 (HO-2) inhibitor with IC₅₀ values of 0.9 μM and 14.9 μM against HO-2 and HO-1, respectively .

HY-118487

OB-24 2 Publications Verification	Heme Oxygenase (HO) Reactive Oxygen Species (ROS)	Cancer
OB-24 is a selective small-molecule HO-1 inhibitor (IC₅₀ = 1.9 μM for HO-1 and IC₅₀ for HO-2 >100 μM). OB-24 possesses anti-tumor and anti-metastatic properties. OB-24 can be studies in research such as prostate cancer, melanoma, ovarian carcinoma and lung metastasis ^[2].

HY-105191

Azalanstat RS-21607	Cytochrome P450 Reactive Oxygen Species (ROS)	Metabolic Disease
Azalanstat (RS-21607) is an inhibitor of heme oxygenase and lanosterol 14α-demethylase, with inhibitory activity against HO-1 (IC₅₀ = 5.5 µM) and *HO-2* (IC₅₀ = 24.5 µM). Azalanstat reduces the maturation rate of rat oocytes, increases rat oocyte degeneration, and partially inhibits progesterone production in preovulatory follicles of rats ^[2] .

HY-RS06250

HMOX2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HMOX2 Human Pre-designed siRNA Set A contains three designed siRNAs for HMOX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HMOX2 Human Pre-designed siRNA Set A HMOX2 Human Pre-designed siRNA Set A

HY-RS24009

Hmox2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Hmox2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hmox2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Hmox2 Rat Pre-designed siRNA Set A Hmox2 Rat Pre-designed siRNA Set A

HY-182604

QC-308	Heme Oxygenase (HO)	Cancer
QC-308 is a HO-1/HO-2 inhibitor with an HO-1 IC₅₀ of 0.27 μM and an *HO-2* IC₅₀ of 0.46 μM. QC-308 coordinates heme iron(II) to disrupt catalysis. QC-308 can be used for research of HO-1 inhibition mechanisms in cancer .

HY-105191A

Azalanstat dihydrochloride RS-21607 dihydrochloride	Heme Oxygenase (HO)	Metabolic Disease
Azalanstat dihydrochloride (RS-21607 dihydrochloride) is an inhibitor of heme oxygenase and lanosterol 14α-demethylase, with inhibitory activity against HO-1 (IC₅₀ = 5.5 µM) and *HO-2* (IC₅₀ = 24.5 µM). Azalanstat dihydrochloride reduces the maturation rate of rat oocytes, increases rat oocyte degeneration, and partially inhibits progesterone production in preovulatory follicles of rats ^[2] .

HY-RS17550

Hmox2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Hmox2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hmox2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Hmox2 Mouse Pre-designed siRNA Set A Hmox2 Mouse Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P79126

	HO-2/HMOX2 Protein, Human (His) HMOX2; HO-2; HO2; Heme Oxygenase 2	Human	E. coli
	Through its catalytic activity, HO-2/HMOX2 protein promotes the oxidative cleavage of heme at the α-methylene bridge carbon, thereby releasing carbon monoxide (CO). This process simultaneously produces biliverdin IXalpha and releases the central heme iron chelate in the form of ferrous iron. HO-2/HMOX2 Protein, Human (His) is the recombinant human-derived HO-2/HMOX2 protein, expressed by E. coli , with C-6*His labeled tag.

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Host:	Mouse (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (2) ICC/IF (2) FC (2)
Isotype:	IgG2b (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88085

	HMOX2 (Heme oxygenase 2) Antibody (YA7769) HO-2	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	HMOX2 (Heme oxygenase 2) Antibody (YA7769) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HMOX2 (Heme oxygenase 2).

HY-P88085A

	HMOX2 (Heme oxygenase 2) Antibody (YA7769)(PBS only) HO-2	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	HMOX2 (Heme oxygenase 2) Antibody (YA7769) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HMOX2 (Heme oxygenase 2).

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Cat. No.	Product Name		Classification

HY-RS06250

HMOX2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
HMOX2 Human Pre-designed siRNA Set A contains three designed siRNAs for HMOX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS24009

Hmox2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Hmox2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hmox2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17550

Hmox2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Hmox2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hmox2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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