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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
Hep G‐2
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "Hep G‐2" in MCE Product Catalog:
1
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Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis .
Cat. No.: HY-N7152
CAS No.: 76060-35-0
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Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae
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Cat. No.: HY-144666
Purity: 99.64%
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GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor. GLS-1-IN-1 shows inhibitory effect against Hep G2, MCF 7, and MCF 10A cells .
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Cat. No.: HY-N8954
CAS No.: 17353-03-6
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Cat. No.: HY-N8882
CAS No.: 60539-23-3
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Cat. No.: HY-N7273
CAS No.: 55304-02-4
Category:
Triterpenes Leguminosae Glycine max (L.) merr Terpenoids Plants Disease Research Fields Cancer
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Cat. No.: HY-146189
CAS No.: 2413901-61-6
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Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor 9 is also a classical DNA-intercalator with an IC50 of 43.51 μM. Topoisomerase II inhibitor 9 arrests the cell cycle at the G2/M phase and induces apoptosis in Hep G‐2 cells .
Antioxidant agent-15 (Compound 4) is a potent antioxidant inhibition activity, with the IC50 of 15.44 nM. Antioxidant agent-15 inhibits tumor cell growth in Hela, Hep G2 and Caco-2 cells, with the IC50 of 395.26, 400.4 and 24.6 nM, respectively .
Cat. No.: HY-N10023
CAS No.: 120849-18-5
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Cat. No.: HY-N2298
CAS No.: 109232-77-1
Category:
Adinandra nitida Merr. ex Li Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Cancer Theaceae
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Cat. No.: HY-117219
CAS No.: 136209-43-3
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SKF 104976 is a 3,2-carboxylic acid derivative with potent 14-alpha-demethylase (14 alpha DM) inhibitory activity. SKF 104976 inhibited 14 alpha DM activity by 50% at 2 nM in Hep G2 cell extracts. SKF 104976 inhibited the incorporation of [14C]acetate into cholesterol in intact cells at similar concentrations, accompanied by accumulation of lanosterol, and resulted in a 40-70% decrease in 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) activity. SKF 104976 did not affect the uptake and degradation of low-density lipoprotein in Hep G2 cells, indicating that HMGR and low-density lipoprotein receptor activities are not coordinately regulated under these conditions. The inhibitory effect of SKF 104976 on HMGR activity remained unchanged even when the flux of carbon units in the sterol synthesis pathway was reduced by 80%. SKF 104976 did not inhibit HMGR activity under conditions where sterol synthesis was almost completely blocked by lovastatin .
Cat. No.: HY-N15577
CAS No.: 1859979-00-2
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Cat. No.: HY-145290
CAS No.: 2968315-02-6
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CPT-Se3, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT–Se3 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se3 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.19-4.7 μM) .
Cat. No.: HY-145291
CAS No.: 2968315-03-7
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CPT-Se4, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT-Se4 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se4 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.54-6.4 μM) .
Cat. No.: HY-118518
CAS No.: 85247-77-4
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Ronipamil is a calcium ion antagonist. Ronipamil increases the specific binding and internalization of human 125I-LDL in human skin fibroblasts (HSF) and the human hepatoma cell line Hep G2 .
Cat. No.: HY-N16642
CAS No.: 155969-81-6
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Cat. No.: HY-W754691
CAS No.: 6808-72-6
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Cat. No.: HY-N3093
CAS No.: 1025023-05-5
Synonyms: (+)-Periglaucine B
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Cat. No.: HY-N15392
CAS No.: 709032-67-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
