5 Results for "

Hit1

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Hit1" in MCE Product Catalog:

Cat. No.: HY-143401
CAS No.: 2785377-42-4
Target:  

IDE

Research Areas:  

Metabolic Disease

Hit 1 is an activator of ansulin degrading enzyme (IDE), with an EC50 of 5.5 μM. Hit 1 can decrease glucose-stimulating insulin secretion [1].
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Cat. No.: HY-148545
CAS No.: 330638-43-2
Target:  

SHMT

Research Areas:  

Cancer

SHMT-IN-3 (Hit 1) is a SHMT1 and SHMT2 inhibitor with an IC50 of 0.53 µM for human SHMT1. SHMT-IN-3 exhibits noncompetitive inhibition against serine [1].
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Cat. No.: HY-174842
CAS No.: 696643-14-8
HTS05585 (Compound Hit-1) is a selective macrophage migration inhibitory factor (MIF) inhibitor with a Kd value of 0.29 μM measured by microscale thermophoresis (MST) and 0.32±0.01 μM verified by isothermal titration calorimetry (ITC). HTS05585 inhibits the release of pro-inflammatory factors (TNF-α, IL-6, IL-1β) from LPS-induced macrophages. HTS05585 is promising for research of inflammation-related diseases such as sepsis [1].
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Cat. No.: HY-RS16182
Research Areas:  

Others

ZNHIT3 Human Pre-designed siRNA Set A contains three designed siRNAs for ZNHIT3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-173514
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2 Mpro-IN-42 (compound C5) is a potent SARS-CoV-2 Mpro inhibitor with an IC50 of 33.6 nM. SARS-CoV-2 Mpro-IN-42 can be used in the study of SARS-CoV-2 [1].
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