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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Hrd1
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Hrd1" in MCE Product Catalog:
3
Target:
Research Areas:
Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy [1] .
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1 Cited Publications
Cat. No.: HY-49116
CAS No.: 500285-30-3
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CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress [1].
Cat. No.: HY-160700
CAS No.: 2839740-79-1
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Research Areas:
TNG348 is an orally available allosteric inhibitor of the ubiquitin-specific protease USP1. TNG348 specifically and efficiently inhibits the activity of USP1, inhibiting its deubiquitination of proliferative PCNA and FANCD2, thereby disrupting the DNA repair process. TNG348 has inhibitory activity against breast and ovarian cancers carrying BRCA1/2 mutations and other homologous recombination defects (HRD) .
Cat. No.: HY-B0124A
CAS No.: 68291-98-5
Synonyms: AD 810 sodium; CI 912 sodium
Target:
Research Areas:
Zonisamide (AD 810) sodium is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide sodium exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide sodium also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide sodium can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy [1] .
Cat. No.: HY-B0124R
CAS No.: 68291-97-4
Synonyms: AD 810 (Standard); CI 912 (Standard)
Research Areas:
Zonisamide (Standard) is the analytical standard of Zonisamide. This product is intended for research and analytical applications. Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy [1] .
Cat. No.: HY-B0124S2
Synonyms: AD 810-13C6; CI 912-13C6
Cat. No.: HY-W018161R
CAS No.: 505-54-4
Synonyms: Thapsic acid (Standard)
Cat. No.: HY-RS14127
Target:
Research Areas:
SYVN1 Human Pre-designed siRNA Set A contains three designed siRNAs for SYVN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18845
Target:
Research Areas:
Syvn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Syvn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W018161S
CAS No.: 130348-90-2
Cat. No.: HY-B0124S3
CAS No.: 2308764-57-8
Cat. No.: HY-P87091
Synonyms: 1200010C09Rik antibody; DER3 antibody; E3 ubiquitin-protein ligase synoviolin antibody; HMG coA reductase degradation 1 homolog antibody; Hrd1 antibody; KIAA1810 antibody; MGC40372 antibody; OTTHUMP00000230429 antibody; OTTHUMP00000230430 antibody; OTTHUMP00000230431 antibody; 1200010C09Rik antibody; DER3 antibody; E3 ubiquitin-protein ligase synoviolin antibody; HMG coA reductase degradation 1 homolog antibody; Hrd1 antibody; KIAA1810 antibody; MGC40372 antibody; OTTHUMP00000230429 antibody; OTTHUMP00000230430 antibody; OTTHUMP00000230431 antibody; OTTHUMP00000230432 antibody; Synovial apoptosis inhibitor 1 antibody; Synovial apoptosis inhibitor 1, synoviolin antibody; Synoviolin 1 antibody; Synoviolin 1 isoform b antibody; SYNOVIOLIN antibody; SYVN1 antibody; SYVN1_HUMAN antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
