12 Results for "

IGF-IR

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "IGF-IR" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-13020
CAS No.: 1116235-97-2
Purity:  99.58%
GSK1838705A is a potent and reversible IGF-IR and the insulin receptor inhibitor with IC50s of 2.0 and 1.6 nM, respectively. It also inhibits ALK with an IC50 of 0.5 nM.
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2
2 Cited Publications
Cat. No.: HY-13686
CAS No.: 196868-63-0
Purity:  99.85%
Target:  

IGF-1R Apoptosis

Research Areas:  

Cancer

PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis .
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Cat. No.: HY-P99189
CAS No.: 947687-12-9
Synonyms: IMC-A12; NSC742460

Target:  

IGF-1R

Research Areas:  

Cancer

Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer .
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Cat. No.: HY-RS06615
Research Areas:  

Others

IGF1R Human Pre-designed siRNA Set A contains three designed siRNAs for IGF1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P11620
CAS No.: 290810-63-8
Target:  

Drug Derivative

Research Areas:  

Others

H-Asn-Pro-Glu-Tyr(PO3H2)-OH is a phosphorylated peptide derivative of the tetramine motif Asn-Pro-Glu-Tyr (NPEY), and is a substrate binding domain common to the insulin-like growth factor-I receptor (IGF-IR) and the insulin receptor (IR).
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Cat. No.: HY-P78458
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD221; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216
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Cat. No.: HY-P78142
Purity:  ≥ 90%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: CD221; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216
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Cat. No.: HY-P704676
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221
Species:  
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Cat. No.: HY-P72606
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221
Species:  
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Cat. No.: HY-P72256
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD221; CD221 antigen ; IGF 1 receptor; IGF 1R; IGF I receptor; IGF-I receptor; IGF1r; IGF1R_HUMAN; IGFIR; IGFIRC; IGFR; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; MGC142170; MGC142172; MGC18216; Soluble IGF1R variant 1; Soluble IGF1R variant 2
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Cat. No.: HY-P74442
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R
Species:  
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Cat. No.: HY-P73137
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R
Species:  
Source:  
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