15 Results for "

IGF-IR

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "IGF-IR" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-13020
CAS No.: 1116235-97-2
Purity:  99.58%
GSK1838705A is a potent and reversible IGF-IR and the insulin receptor inhibitor with IC50s of 2.0 and 1.6 nM, respectively. It also inhibits ALK with an IC50 of 0.5 nM.
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2
2 Cited Publications
Cat. No.: HY-13686
CAS No.: 196868-63-0
Purity:  99.85%
Target:  

IGF-1R Apoptosis

Research Areas:  

Cancer

PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis .
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2
2 Cited Publications
Cat. No.: HY-P78723
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; IGFR; IGF1R Protein
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P99189
CAS No.: 947687-12-9
Synonyms: IMC-A12; NSC742460

Target:  

IGF-1R

Research Areas:  

Cancer

Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer .
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Cat. No.: HY-RS06615
Research Areas:  

Others

IGF1R Human Pre-designed siRNA Set A contains three designed siRNAs for IGF1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P11620
CAS No.: 290810-63-8
Target:  

Drug Derivative

Research Areas:  

Others

H-Asn-Pro-Glu-Tyr(PO3H2)-OH is a phosphorylated peptide derivative of the tetramine motif Asn-Pro-Glu-Tyr (NPEY), and is a substrate binding domain common to the insulin-like growth factor-I receptor (IGF-IR) and the insulin receptor (IR).
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Cat. No.: HY-P704676
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78458
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72606
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78142
Purity:  ≥ 90%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72256
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P74442
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P73137
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P78724
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P78586
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin Like Growth Factor 1 Receptor; MGC18216; Insulin-Like Growth Factor 1 Receptor; Insulin-Like Growth Factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; I
Species:  
Cynomolgus
Source:  
HEK293
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