56 Results for "

IL-7

" in MedChemExpress (MCE) Product Catalog:
Products (56)

56 Results for "IL-7" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P7045
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7; IL7 Nirs Variant 5; Interleukin 7; IL7 Nirs Variant 3; IL-7; IMD130; Interleukin-7
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P73226
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7; IL7 Nirs Variant 5; Interleukin 7; IL7 Nirs Variant 3; IL-7; IMD130; Interleukin-7
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P99412
CAS No.: 2375835-91-7
Synonyms: OSE-127

Target:  

Interleukin Related

Research Areas:  

Cancer

Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research .
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1
1 Cited Publications
Cat. No.: HY-P990210

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse/Human IL-7 Antibody (M25) is an anti-mouse IL-7 IgG2b monoclonal antibody. Anti-Mouse/Human IL-7 Antibody (M25) alleviates inflammation by blocking IL-7 signaling and inhibiting innate lymphoid cells (ILC2s) activation. Anti-Mouse/Human IL-7 Antibody (M25) can reduce the number of B cell precursors. Anti-Mouse/Human IL-7 Antibody (M25) can be used for researches on inflammation conditions such as airway inflammation .
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1
1 Cited Publications
Cat. No.: HY-P990209
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .
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1
1 Cited Publications
Cat. No.: HY-P700217AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7; IL7 Nirs Variant 5; Interleukin 7; IL7 Nirs Variant 3; IL-7; IMD130; Interleukin-7
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-P99908
CAS No.: 2026634-47-7
Synonyms: NT-17

Target:  

Interleukin Related

Research Areas:  

Cancer

Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 + and CD8 + cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .
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Cat. No.: HY-P990023
CAS No.: 2622254-57-1
Synonyms: ADX-914
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Bempikibart (ADX-914) is a fully human IgG1-κ monoclonal antibody targeting IL-7Rα. Bempikibart binds to the IL-7 receptor alpha and blocks IL-7 and TSLP signaling. Bempikibart reduces T cell populations while relatively preserving regulatory T cells. Bempikibart inhibits Th1, Th2, and Th17 immune pathways. Bempikibart can be used in research on alopecia areata and atopic dermatitis .
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Cat. No.: HY-P991424

Research Areas:  

Inflammation/Immunology

GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used for the research of autoimmune and allergic inflammatory diseases. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P990911
CAS No.: 2893793-17-2
Synonyms: ZB-168

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

HY-P990911 is an IL7R-targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control (HY-P990096) .
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Cat. No.: HY-P990647

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

PF-06342674 is a CHO-expressed humanized antibody that targets IL-7Ra/CD127. PF-06342674 carries a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145.14 kDa. The isotype control for PF-06342674 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS06779
Research Areas:  

Others

IL7 Human Pre-designed siRNA Set A contains three designed siRNAs for IL7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174598
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL7 mRNA encodes the human interleukin 7 (IL7) protein, a cytokine that is important for B and T cell development. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells.
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Cat. No.: HY-RS23475
Research Areas:  

Others

Il7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17031
Research Areas:  

Others

Il7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174597
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.
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Cat. No.: HY-P991720
CAS No.: 2985643-31-8

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Tepilukimig is a bivalent humanized IgG1κ monoclonal antibody inhibitor targeting TSLP-IL7Rα and TSLP-CRLF2. Tepilukimig inhibits the binding of TSLP to its receptors (IL7Rα and CRLF2) on the cell surface, thereby completely interrupting the inflammatory signaling pathway driven by TSLP. Tepilukimig can be used for allergic and inflammatory diseases like atopic dermatitis and asthma research .
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Cat. No.: HY-P73227A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7; IL7 Nirs Variant 5; Interleukin 7; IL7 Nirs Variant 3; IL-7; IMD130; Interleukin-7
Species:  
Rat
Source:  
E. coli
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Cat. No.: HY-P73227
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7; IL7 Nirs Variant 5; Interleukin 7; IL7 Nirs Variant 3; IL-7; IMD130; Interleukin-7
Species:  
Rat
Source:  
E. coli
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