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Isoforms Recommended: IL-7
Results for "

IL-7

" in MedChemExpress (MCE) Product Catalog:

24

Inhibitors & Agonists

1

Peptides

14

Inhibitory Antibodies

31

Recombinant Proteins

4

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99412
    Lusvertikimab
    1 Publications Verification

    OSE-127

    Interleukin Related Cancer
    Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research .
    Lusvertikimab
  • HY-P990774

    ASP-7266; TRAB-1; UPB-101

    Interleukin Related Inflammation/Immunology
    Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
    Verekitug
  • HY-P99908

    NT-17

    Interleukin Related Cancer
    Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 + and CD8 + cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .
    Efineptakin alfa
  • HY-P99351

    Anti-MMP9 Reference Antibody (andecaliximab)

    MMP Cancer
    Andecaliximab is a recombinant chimeric IgG4 monoclonal antibody (mAb) targets matrix metalloproteinase 9 (MMP9). Andecaliximab shows the antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. Andecaliximab can be used for the research of gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF) .
    Andecaliximab
  • HY-P990210
    Anti-Mouse/Human IL-7 Antibody (M25)
    1 Publications Verification

    Interleukin Related Inflammation/Immunology
    Anti-Mouse/Human IL-7 Antibody (M25) is an anti-mouse IL-7 IgG2b monoclonal antibody. Anti-Mouse/Human IL-7 Antibody (M25) alleviates inflammation by blocking IL-7 signaling and inhibiting innate lymphoid cells (ILC2s) activation. Anti-Mouse/Human IL-7 Antibody (M25) can reduce the number of B cell precursors. Anti-Mouse/Human IL-7 Antibody (M25) can be used for researches on inflammation conditions such as airway inflammation .
    Anti-Mouse/Human IL-7 Antibody (M25)
  • HY-P990023

    ADX-914

    Interleukin Related Metabolic Disease Inflammation/Immunology
    Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .
    Bempikibart
  • HY-P991424

    Interleukin Related STAT Inflammation/Immunology
    GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used for the research of autoimmune and allergic inflammatory diseases. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
    GSK2618960
  • HY-P990209

    Interleukin Related Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .
    Anti-Mouse IL-7Rα/CD127 Antibody (A7R34)
  • HY-P990911

    ZB-168

    Interleukin Related Inflammation/Immunology
    HY-P990911 is an IL7R-targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control (HY-P990096) .
    Crebankitug
  • HY-P990647

    Interleukin Related Inflammation/Immunology
    PF-06342674 is a CHO-expressed humanized antibody that targets IL-7Ra/CD127. PF-06342674 carries a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145.14 kDa. The isotype control for PF-06342674 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
    PF-06342674
  • HY-RS06779

    Small Interfering RNA (siRNA) Others

    IL7 Human Pre-designed siRNA Set A contains three designed siRNAs for IL7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    IL7 Human Pre-designed siRNA Set A
    IL7 Human Pre-designed siRNA Set A
  • HY-174598

    mRNA Inflammation/Immunology
    Human IL7 mRNA encodes the human interleukin 7 (IL7) protein, a cytokine that is important for B and T cell development. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells.
    Human IL7 mRNA
  • HY-RS23475

    Small Interfering RNA (siRNA) Others

    Il7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Il7 Rat Pre-designed siRNA Set A
    Il7 Rat Pre-designed siRNA Set A
  • HY-RS17031

    Small Interfering RNA (siRNA) Others

    Il7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Il7 Mouse Pre-designed siRNA Set A
    Il7 Mouse Pre-designed siRNA Set A
  • HY-174597

    mRNA Inflammation/Immunology
    Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.
    Human IL7R mRNA
  • HY-P991720

    Interleukin Related Inflammation/Immunology
    Tepilukimig is a bivalent humanized IgG1κ monoclonal antibody inhibitor targeting TSLP-IL7Rα and TSLP-CRLF2. Tepilukimig inhibits the binding of TSLP to its receptors (IL7Rα and CRLF2) on the cell surface, thereby completely interrupting the inflammatory signaling pathway driven by TSLP. Tepilukimig can be used for allergic and inflammatory diseases like atopic dermatitis and asthma research .
    Tepilukimig
  • HY-P990292

    Interleukin Related Metabolic Disease Inflammation/Immunology Cancer
    Anti-Mouse CD132 (common γ chain) Antibody (3E12) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse CD132. Anti-Mouse CD132 (common γ chain) Antibody (3E12) can block IL-2, IL-4 and IL-7. Anti-Mouse CD132 (common γ chain) Antibody (3E12) can inhibit T cells and B cells. Anti-Mouse CD132 (common γ chain) Antibody (3E12) can be used for the researches of cancer, immunology, inflammation and metabolic disease, such as tumor, skin transfer and diabetes .
    Anti-Mouse CD132 (common γ chain) Antibody (3E12)
  • HY-RS06780

    Small Interfering RNA (siRNA) Others

    IL7R Human Pre-designed siRNA Set A contains three designed siRNAs for IL7R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    IL7R Human Pre-designed siRNA Set A
    IL7R Human Pre-designed siRNA Set A
  • HY-RS16894

    Small Interfering RNA (siRNA) Others

    Il7r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Il7r Mouse Pre-designed siRNA Set A
    Il7r Mouse Pre-designed siRNA Set A
  • HY-167153

    Interleukin Related Reactive Oxygen Species (ROS) Cardiovascular Disease Neurological Disease Inflammation/Immunology
    PNA5 is a novel, blood-brain barrier permeable glycosylated angiotensin-(1-7) peptide and MasR agonist. PNA5 inhibits IL-7, increases IL-10. PNA5 inhibits ROS generation, decreases Iba-1 expression. PNA5 exhibits sustained cognitive protective effects. PNA5 rescues blunted cerebral functional hyperemia. PNA5 can be used in the research of inflammation-related brain diseases .
    PNA5
  • HY-RS23336

    Small Interfering RNA (siRNA) Others

    Il7r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Il7r Rat Pre-designed siRNA Set A
    Il7r Rat Pre-designed siRNA Set A
  • HY-P991265

    Interleukin Related Cancer
    OSE-703 is a humanized monoclonal antibody inhibitor targeting interleukin-7 receptor α subunit (IL-7Rα). OSE-703 is promising for research of tumors and respiratory diseases .
    OSE-703
  • HY-206870

    Interleukin Related STAT Inflammation/Immunology
    BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks TSLPR-IL7Rα co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6. BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis .
    BP79
  • HY-P992447

    Interleukin Related Inflammation/Immunology
    QX008N is a humanized IgG1 monoclonal antibody and also a TSLP inhibitor with a KD value of 0.0175 nM. QX008N blocks TSLP-induced signaling pathways by inhibiting the interaction of TSLP-TSLPR-IL-7Rα. QX008N reduces eosinophil and IgE levels, improves pulmonary function, blocks TSLP-induced inflammation, and enhances the inhibitory effect on inflammatory mediators when administered in combination with anti-IL-4R antibodies. QX008N is applicable to relevant research on asthma .
    QX008N

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