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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
IL31
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "IL31" in MCE Product Catalog:
1
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1
1 Cited Publications
Cat. No.: HY-19522C
CAS No.: 928821-40-3
Synonyms: MBX-8025 (lysine dihydrate); RWJ-800025 (lysine dihydrate)
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Seladelpar Lysine dihydrate (MBX-8025 lysine dihydrate) is an orally active, selective PPAR-δ agonist with an EC50 of 2 nM against hPPAR-δ. Seladelpar Lysine dihydrate reduces serum IL-31 and bile acid levels. It alleviates pruritus symptoms. Seladelpar Lysine dihydrate enhances insulin sensitivity, normalizes levels of hyperglycemia, hyperinsulinemia, glucose disposal capacity, serum lipids and hepatic free cholesterol. It reduces steatosis, hepatic inflammation and improves liver fibrosis. Seladelpar Lysine dihydrate reverses the pathological changes of non-alcoholic steatohepatitis (NASH). It is applicable to research related to primary biliary cholangitis and non-alcoholic steatohepatitis (NASH) .
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Cat. No.: HY-P99162
CAS No.: 1476039-58-3
Synonyms: CIM331; CD14152
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Cat. No.: HY-P99301
CAS No.: 1533403-95-0
Synonyms: Anti-Canine IL31 Recombinant Antibody; CAN34D3-65; PF-06443537
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Atinvicitinib is an orally active and selective JAK1 inhibitor. Atinvicitinib blocks signaling of JAK1-dependent pruritogenic and pro-inflammatory cytokines, including those in the IL-31, IL-4, and IL-13 pathways. Atinvicitinib can be used for the researches of pruritus associated with allergic dermatitis and canine atopic dermatitis .
Cat. No.: HY-P991280
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Cat. No.: HY-170415
CAS No.: 1700655-93-1
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EGR-1 IN-3 (Compound 36) is an early growth response 1 (EGR-1)-DNA binding disruptor. EGR-1-IN-3 inhibits TNFα-induced binding of EGR-1 to DNA and expression of genes associated with inflammation (such as TSLP, IL-31, IL-6 and CCL2). EGR-1-IN-3 can be used in the study of inflammatory diseases .
Cat. No.: HY-P990713
CAS No.: 2750248-93-0
Synonyms: VTQ-2101
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Cat. No.: HY-P99557
CAS No.: 2364504-80-1
Synonyms: KIND-016
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Cat. No.: HY-156959
CAS No.: 19683-98-8
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Ovalicin is a multi-target inhibitor that targets MetAP2, HRH2, JAK2 and TRPV1, with anti-inflammatory and anti-atopic dermatitis activities. Ovalicin covalently binds to MetAP2 to inhibit its function, thereby blocking the replication of Enterocytozoon bieneusi and Vittaforma corneae. Ovalicin alleviates intestinal injury and prolongs survival in infected mouse models, without showing obvious hepatorenal toxicity. Ovalicin attenuates LPS-induced calcium influx, reduces the infiltration of macrophages and mast cells in the skin, and regulates the expression of inflammation-related genes such as IL-31, effectively relieving allergic symptoms in mouse models. Ovalicin can be used for the research of microsporidiosis and atopic dermatitis .
Cat. No.: HY-RS06754
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IL31 Human Pre-designed siRNA Set A contains three designed siRNAs for IL31 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24213
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Il31 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il31 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174609
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Human IL31 mRNA encodes the human interleukin 31 (IL31) protein, which may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.
Cat. No.: HY-RS17747
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Il31 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il31 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P99864
CAS No.: 2171034-71-0
Synonyms: ZTS-00521505
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Cat. No.: HY-P700207AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL31; IL-31; Interleukin-31
Cat. No.: HY-P992247
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
