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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
IL31
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "IL31" in MCE Product Catalog:
1
1 Cited Publications
Art. -Nr.: HY-P99519
CAS. Nr.: 2243320-83-2
Synonyms: KPL-716; BIIB-069; RG-6536
Target:
Forschungsgebiete:
1
1 Cited Publications
Art. -Nr.: HY-19522C
CAS. Nr.: 928821-40-3
Synonyms: MBX-8025 (lysine dihydrate); RWJ-800025 (lysine dihydrate)
Target:
Forschungsgebiete:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Seladelpar Lysine dihydrate (MBX-8025 lysine dihydrate) is an orally active, selective PPAR-δ agonist with an EC50 of 2 nM against hPPAR-δ. Seladelpar Lysine dihydrate reduces serum IL-31 and bile acid levels. It alleviates pruritus symptoms. Seladelpar Lysine dihydrate enhances insulin sensitivity, normalizes levels of hyperglycemia, hyperinsulinemia, glucose disposal capacity, serum lipids and hepatic free cholesterol. It reduces steatosis, hepatic inflammation and improves liver fibrosis. Seladelpar Lysine dihydrate reverses the pathological changes of non-alcoholic steatohepatitis (NASH). It is applicable to research related to primary biliary cholangitis and non-alcoholic steatohepatitis (NASH) .
1
Art. -Nr.: HY-P99162
CAS. Nr.: 1476039-58-3
Synonyms: CIM331; CD14152
Target:
Forschungsgebiete:
Art. -Nr.: HY-P99301
CAS. Nr.: 1533403-95-0
Synonyms: Anti-Canine IL31 Recombinant Antibody; CAN34D3-65; PF-06443537
Target:
Forschungsgebiete:
Target:
Forschungsgebiete:
Atinvicitinib is an orally active and selective JAK1 inhibitor. Atinvicitinib blocks signaling of JAK1-dependent pruritogenic and pro-inflammatory cytokines, including those in the IL-31, IL-4, and IL-13 pathways. Atinvicitinib can be used for the researches of pruritus associated with allergic dermatitis and canine atopic dermatitis .
Art. -Nr.: HY-P991280
Target:
Forschungsgebiete:
Art. -Nr.: HY-170415
CAS. Nr.: 1700655-93-1
Target:
Forschungsgebiete:
EGR-1 IN-3 (Compound 36) is an early growth response 1 (EGR-1)-DNA binding disruptor. EGR-1-IN-3 inhibits TNFα-induced binding of EGR-1 to DNA and expression of genes associated with inflammation (such as TSLP, IL-31, IL-6 and CCL2). EGR-1-IN-3 can be used in the study of inflammatory diseases .
Art. -Nr.: HY-P990713
CAS. Nr.: 2750248-93-0
Synonyms: VTQ-2101
Target:
Forschungsgebiete:
Art. -Nr.: HY-156959
CAS. Nr.: 19683-98-8
Target:
Forschungsgebiete:
Ovalicin is a multi-target inhibitor that targets MetAP2, HRH2, JAK2 and TRPV1, with anti-inflammatory and anti-atopic dermatitis activities. Ovalicin covalently binds to MetAP2 to inhibit its function, thereby blocking the replication of Enterocytozoon bieneusi and Vittaforma corneae. Ovalicin alleviates intestinal injury and prolongs survival in infected mouse models, without showing obvious hepatorenal toxicity. Ovalicin attenuates LPS-induced calcium influx, reduces the infiltration of macrophages and mast cells in the skin, and regulates the expression of inflammation-related genes such as IL-31, effectively relieving allergic symptoms in mouse models. Ovalicin can be used for the research of microsporidiosis and atopic dermatitis .
Art. -Nr.: HY-RS06754
Target:
Forschungsgebiete:
IL31 Human Pre-designed siRNA Set A contains three designed siRNAs for IL31 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P99557
CAS. Nr.: 2364504-80-1
Synonyms: KIND-016
Target:
Forschungsgebiete:
Tirnovetmab (KIND-016) is an anti-IL-31 monoclonal antibody. Tirnovetmab ameliorates canine allergic dermatitis and atopic dermatitis. Tirnovetmab can be used in research on canine allergic and atopic dermatitis .
Art. -Nr.: HY-RS24213
Target:
Forschungsgebiete:
Il31 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il31 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-174609
Target:
Forschungsgebiete:
Human IL31 mRNA encodes the human interleukin 31 (IL31) protein, which may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.
Art. -Nr.: HY-RS17747
Target:
Forschungsgebiete:
Il31 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il31 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P99864
CAS. Nr.: 2171034-71-0
Synonyms: ZTS-00521505
Target:
Forschungsgebiete:
Art. -Nr.: HY-P992247
Target:
Forschungsgebiete:
Art. -Nr.: HY-P704391
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL31; IL-31; Interleukin 31; Interleukin-31
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P700123AF
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL31; IL-31; Interleukin 31; Interleukin-31
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
