27 Results for "

ILT3

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "ILT3" in MCE Product Catalog:

Cat. No.: HY-P990462

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-LILRB4/ILT3/CD85k Antibody is a CHO-expressed humanized antibody that targets LILRB4/ILT3/CD85k. The predicted molecular weight (MW) of Anti-LILRB4/ILT3/CD85k Antibody is 144.36 kDa.
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Cat. No.: HY-P991307

Research Areas:  

Cancer

BND-35 is a human monoclonal antibody (mAb) targeting LILRB4/ILT3/CD85k. BND-35 blocks the interaction of ILT3 with APOE and fibronectin, enhances the pro-inflammatory activity of various myeloid cells, and reverses ILT3-mediated immunosuppression of T cells by various suppressive myeloid cells. BND-35 has anti-tumor activity in the hILT3 transgenic mouse tumor model .
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Cat. No.: HY-P991308

Research Areas:  

Infection Cancer

TRX385 is a human monoclonal antibody (mAb) targeting LILRB4/ILT3/CD85k. TRX385 can be used in anticancer and antiviral research .
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Cat. No.: HY-184157
IB15C is an ILT3 (LILRB4) inhibitor with a human Kd of 0.92 μM. IB15C binds to a specific ILT3 pocket, disrupts ApoE interaction, and interferes with downstream inhibitory signaling pathways. IB15C reduces SHP1 and SHP2 phosphorylation, suppresses pro-inflammatory cytokine secretion, enhances amyloid uptake, and attenuates NF-κB activation. IB15C can be used for the research of alzheimer's disease .
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Cat. No.: HY-P84679A
Synonyms: ILT3; LIR5; LILRB4; ILT-3; LIR-5

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84679
Synonyms: ILT3; LIR5; LILRB4; ILT-3; LIR-5

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P704762
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P77738
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P77743
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P705056
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P77744
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P701065
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P704249
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P700780
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P701064
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P700779
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P701018
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Species:  
Source:  
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Cat. No.: HY-P78645
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LILRB4; ILT3; LIR5; CD85K; HM18
Species:  
Source:  
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Cat. No.: HY-P78646
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LILRB4; ILT3; LIR5; CD85K; HM18
Species:  
Source:  
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Cat. No.: HY-P992389

Target:  

LILRB

Research Areas:  

Cancer

IO-202 is a high-affinity LILRB4/ILT3 binder and myeloid checkpoint inhibitor. IO-202 blocks APOE binding and LILRB4 activation to reverse T-cell suppression and enhance T-cell cytotoxicity, while eliminating LILRB4-high-expressing leukemic blasts via ADCC and ADCP mechanisms. IO-202 promotes dendritic cell maturation and antigen presentation, reshapes the phenotype of tumor-associated macrophages, and reduces myeloid-derived suppressor cells. IO-202 is widely applicable to research on relapsed/refractory acute myeloid leukemia (AML), chronic myelomonocytic leukemia (CMML), and solid tumors [3].
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