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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
In-vitro
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "In-vitro" in MCE Product Catalog:
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Research Areas:
Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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1 Cited Publications
Cat. No.: HY-P1663
CAS No.: 272121-15-0
Cat. No.: HY-178920
CAS No.: 676458-63-2
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α-Synuclein-IN-17 (Compound 10) is an α-Synuclein inhibitor, with an IC50 value of 9 μM. α-Synuclein-IN-17 exhibits potent inhibitory activity against both in-vitro assembled asyn fibrils and LBD brain tissue-amplified asyn fibrils. α-Synuclein-IN-17 can be used for the study of Parkinson's disease (PD) and Lewy Body Disease (LBD) .
Cat. No.: HY-157404
CAS No.: 2918764-16-4
Pim-1/2 kinase inhibitor 2 (compound 5b) is a competitive PIM-1 and PIM-2 kinase inhibitor with IC50s of 1.31 μM and 0.67 μM, respectively. Pim-1/2 kinase inhibitor 2 shows in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer activity against myeloid leukaemia (NFS-60), liver (HepG-2), prostate (PC-3), and colon (Caco-2) cancer cell lines .
Cat. No.: HY-B1057S1
CAS No.: 2747915-60-0
Synonyms: FenazoxIne-d4 hydrochloride
Cat. No.: HY-178994
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DENV-IN-14 (Compound 3c) is a thiazole hydrazone derivative with anti-dengue virus (DENV) activity with an EC50 of 0.01 μM and the selectivity index (SI) of 200. DENV-IN-14 exhibits rapid plasma clearance and its metabolic stability is limited. DENV-IN-14 can be used for research on dengue fever .
Cat. No.: HY-N0577R
CAS No.: 26544-34-3
Synonyms: ApigenIn 7-O-apiosylglucoside (Standard); ApigenIn 7-(2-O-apiosylglucoside) (Standard)
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Cat. No.: HY-133115
CAS No.: 46868-19-3
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Research Areas:
N-Desmethylnefopam is the main metabolite of Nefopam. N-Desmethylnefopam is a centrally-acting but non-opioid analgesic agent, for the relief of moderate to severe pain. Nefopam targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
Cat. No.: HY-B1057S
CAS No.: 1346603-30-2
Synonyms: FenazoxIne-d3 hydrochloride
Cat. No.: HY-B1057R
CAS No.: 23327-57-3
Synonyms: FenazoxIne hydrochloride (Standard)
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Research Areas:
Nefopam (hydrochloride) (Standard) is the analytical standard of Nefopam (hydrochloride). This product is intended for research and analytical applications. Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
Cat. No.: HY-W015618R
CAS No.: 89-74-7
Cat. No.: HY-133115S
CAS No.: 2748500-28-7
Cat. No.: HY-115905
CAS No.: 2914224-54-5
Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity .
Cat. No.: HY-K6023
MCE ECM Gentle Dissociation Solution is a gentle ECM-degrading enzyme mixture derived from marine bacteria and Bacillus species, specifically formulated for efficient and low-damage digestion of in-vitro cell systems. It selectively degrades extracellular matrix components while minimizing disruption to the cell membrane and intercellular junctions, thereby significantly reducing mechanical stress during dissociation.
Cat. No.: HY-K6022
MCE ECM Gentle Dissociation Solution is a gentle ECM-degrading enzyme mixture derived from marine bacteria and Bacillus species, specifically formulated for efficient and low-damage digestion of in-vitro cell systems. It selectively degrades extracellular matrix components while minimizing disruption to the cell membrane and intercellular junctions, thereby significantly reducing mechanical stress during dissociation. This product is compatible with a wide range of cell types, including stem cell colonies, primary cells, neural cells, and organoids, and is particularly well suited for gentle yet effective dissociation of brain organoids and other complex 3D structures.
Cat. No.: HY-P87277
Synonyms: bInds and activates aurora B and C In vivo and In vitro antibody; Chromosomal passenger proteIn antibody; InCE_HUMAN antibody; InCENP antibody; Inner centromere proteIn antibody; Inner centromere proteIn antigens 135/155kDa antibody; Inner centromere proteIn antigens 135kD 155kD antibody; Inner centromere proteIn InCENP antibody
Cat. No.: HY-P87277A
Synonyms: bInds and activates aurora B and C In vivo and In vitro antibody; Chromosomal passenger proteIn antibody; InCE_HUMAN antibody; InCENP antibody; Inner centromere proteIn antibody; Inner centromere proteIn antigens 135/155kDa antibody; Inner centromere proteIn antigens 135kD 155kD antibody; Inner centromere proteIn InCENP antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
