12 Results for "

Itaconate

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Itaconate" in MCE Product Catalog:

94
94 Publications Verification
Cat. No.: HY-112675
CAS No.: 3133-16-2
Purity:  99.92%
Synonyms: 4-OI
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-133870
CAS No.: 2454181-83-8
Purity:  98.01%
Synonyms: ITalk
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology

Itaconate-alkyne (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. Itaconate-alkyne, a functional analogue of Itaconate, exhibits comparable antiinflammatory effect with Itaconate and enables the labeling of bona fide targets of Itaconate . Itaconate-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W041892
CAS No.: 617-52-7
Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora .
loading...
    loading...
Cat. No.: HY-W094214
CAS No.: 7338-27-4
Synonyms: β-Methyl Itaconate
Target:  

Drug Derivative

Research Areas:  

Others

Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative of Itaconic acid (HY-Y0520). Monomethyl itaconate can copolymerize with PEGMA to form pH-sensitive hydrogels .
loading...
    loading...
Cat. No.: HY-W076778
CAS No.: 57718-07-7
Research Areas:  

Others

Monoethyl itaconate is a free radical can be used for polymerization .
loading...
    loading...
Cat. No.: HY-W076778R
CAS No.: 57718-07-7
Research Areas:  

Others

Monoethyl itaconate (Standard) is the analytical standard of Monoethyl itaconate. This product is intended for research and analytical applications. Monoethyl itaconate is a free radical can be used for polymerization[1].
loading...
    loading...
Cat. No.: HY-112675R
CAS No.: 3133-16-2
Synonyms: 4-OI (Standard)
Research Areas:  

Inflammation/Immunology

4-Octyl itaconate (Standard) is the analytical standard of 4-Octyl itaconate. This product is intended for research and analytical applications. 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1[1].
loading...
    loading...
Cat. No.: HY-W750576
4-Octyl itaconate- 13C5 is the 13C-labeled 4-Octyl itaconate.
loading...
    loading...
Cat. No.: HY-112675S
Synonyms: 4-OI-13C5-1
4-Octyl itaconate- 13C5-1 is 13C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
loading...
    loading...
Cat. No.: HY-185447
CAS No.: 3086566-93-7
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Biotin-itaconate is a biotin-labeled itaconic anhydride that targets PD-L1. Biotin-itaconate acts as a biotin probe for in vitro alkylation assays to identify itaconate-modified protein substrates. Biotin-itaconate is applicable to cancer research .
loading...
    loading...
Cat. No.: HY-180529
4-Octyl itaconate-Bn-S-NH2 (Compound 8b) is a vasodilator. 4-Octyl itaconate-Bn-S-NH2 can slowly and stably release H₂S, and it alleviates oxidative stress through an antioxidant reaction that depends on the activation of Nrf2. 4-Octyl itaconate-Bn-S-NH2 inhibits the production of intracellular ROS caused by H₂O₂ damage and the cytotoxicity of cells, and activates potassium channel. 4-Octyl itaconate-Bn-S-NH2 can be used for research on hypertension .
loading...
    loading...
Cat. No.: HY-W143131S
CAS No.: 2751594-46-2
Synonyms: Itaconic Acid Diethyl Ester (stabilized with TBC)-13C5
Diethyl itaconate,98% (stabilized with TBC)- 13C5 (Itaconic Acid Diethyl Ester (stabilized with TBC)- 13C5) is the 13C-labeled Diethyl itaconate,98% (stabilized with TBC) (HY-W143131).
loading...
    loading...
  • 1