617-52-7
617-52-7
Chemical Structure
Dimethyl itaconate
- CAS No.: 617-52-7
- Formula:C7H10O4
- Molecular Weight:158.15
IUPAC Name: dimethyl 2-methylenesuccinate
InChIKey: ZWWQRMFIZFPUAA-UHFFFAOYSA-N
SMILES: C(C(C(OC)=O)=C)C(OC)=O
Biological Activity: Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Dimethyl itaconate | 99.44% | Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Ferreira AV, et al., Dimethyl itaconate induces long-term innate immune responses and confers protection against infection. Cell Rep. 2023 Jun 27;42(6):112658. [Content Brief]
- [2]. Pan W, et al., Dimethyl itaconate ameliorates cognitive impairment induced by a high-fat diet via the gut-brain axis in mice. Microbiome. 2023 Feb 21;11(1):30. [Content Brief]
Keywords
