617-52-7
617-52-7
Chemical Structure
Dimethyl itaconate
- CAS No.: 617-52-7
- Formula:C7H10O4
- Molecular Weight:158.15
IUPAC Name: dimethyl 2-methylenesuccinate
InChIKey: ZWWQRMFIZFPUAA-UHFFFAOYSA-N
SMILES: C(C(C(OC)=O)=C)C(OC)=O
Biological Activity: Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dimethyl itaconate | 99.44% | Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.86
HY-Y1787RDimethyl malonate (Standard) -
Similarity Score 0.85
HY-W094214Monomethyl itaconate -
Similarity Score 0.82
HY-W016801Dimethyl acetone-1,3-dicarboxylate -
Similarity Score 0.82
HY-Y0808Dimethyl succinate -
Similarity Score 0.81
HY-W143131SDiethyl itaconate,98% (stabilized with TBC)-13C5 -
Similarity Score 0.80
HY-W089014Dimethyl glutarate -
Similarity Score 0.78
HY-Y1298RMethyl acetylacetate (Standard) -
Similarity Score 0.78
HY-Y1298SMethyl acetylacetate-13C4 -
Similarity Score 0.78
HY-W076778Monoethyl itaconate -
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References
- [1]. Ferreira AV, et al., Dimethyl itaconate induces long-term innate immune responses and confers protection against infection. Cell Rep. 2023 Jun 27;42(6):112658. [Content Brief]
- [2]. Pan W, et al., Dimethyl itaconate ameliorates cognitive impairment induced by a high-fat diet via the gut-brain axis in mice. Microbiome. 2023 Feb 21;11(1):30. [Content Brief]
