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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
85 Results for "
KLF
" in MedChemExpress (MCE) Product Catalog:
Products (85)
85 Results for "KLF" in MCE Product Catalog:
21
Research Areas:
APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor . APTO-253 has antiarthritic activity .
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16 Cited Publications
Synonyms: 9-Bromopaullone; NSC-664704
Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β, with IC50s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC50s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4, reduces self-renewal of breast cancer stem cells and cell motility in vitro.
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1 Cited Publications
SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 (HY-19994) with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer .
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1 Cited Publications
Cat. No.: HY-W011044
CAS No.: 749872-43-3
CID 5951923 is a potent inhibitor of Krüppel-like factor 5 (KLF5), with an IC50 of 603 nM. CID 5951923 can inhibit proliferation of cancer cells in vitro .
Cat. No.: HY-N1570
CAS No.: 34175-96-7
Category:
other families Ketones, Aldehydes, Acids Plants Disease Research Fields Inflammation/Immunology Pteridium aquilinum Pteridiaceae
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Cat. No.: HY-W181026
CAS No.: 1197834-98-2
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KLF10-IN-1 (#48-15) is a KLF10 inhibitor with an IC50 value of 40 μM for KLF10 reporter gene. KLF10-IN-1 can inhibit KLF10-DNA binding and transcriptional activity, block the conversion of CD4+CD25 T cells to CD4+CD25+T regulatory cells, and inhibit the expression of KLF10 target genes. KLF10-IN-1 can be used as a useful mechanistic probe to study KLF10-mediated effects and T regulatory cell biology .
Cat. No.: HY-RS17539
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Klf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07342
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KLF5 Human Pre-designed siRNA Set A contains three designed siRNAs for KLF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07346
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KLF9 Human Pre-designed siRNA Set A contains three designed siRNAs for KLF9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16607
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Klf4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klf4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23996
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Klf2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Klf2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-131923
CAS No.: 208255-51-0
Cat. No.: HY-N1570R
CAS No.: 34175-96-7
Cat. No.: HY-RS07339
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KLF2 Human Pre-designed siRNA Set A contains three designed siRNAs for KLF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07330
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KLF1 Human Pre-designed siRNA Set A contains three designed siRNAs for KLF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07331
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KLF10 Human Pre-designed siRNA Set A contains three designed siRNAs for KLF10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07332
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KLF11 Human Pre-designed siRNA Set A contains three designed siRNAs for KLF11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
