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Isoforms Recommended:	KLK3

Results for "

KLK3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Kallikrein (1) Androgen Receptor (6) c-Myc (2) Orphan Nuclear Receptor (2) Reference Standards (1) Small Interfering RNA (siRNA) (4)
By Research Areas:	Cancer (4) Endocrinology (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Kallikrein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-135794

11-Ketodihydrotestosterone 1 Publications Verification 11-KDHT; 5α-Dihydro-11-keto testosterone	Androgen Receptor	Endocrinology
11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a K_i of 20.4 nM and an EC₅₀ of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells .

HY-RS07381

KLK3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
KLK3 Human Pre-designed siRNA Set A contains three designed siRNAs for KLK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

KLK3 Human Pre-designed siRNA Set A KLK3 Human Pre-designed siRNA Set A

HY-144127

AR antagonist 3	Androgen Receptor	Cancer
AR antagonist 3 is a potent and selective androgen receptor (AR) antagonist with an IC₅₀ of 0.47 µM. AR antagonist 3 exhibits a dose-dependent decrease of the FRET signal (IC₅₀= 18.05 μM). AR antagonist 3 shows effective inhibition on tumor growth when administered intratumorally .

HY-135794R

11-Ketodihydrotestosterone (Standard) 11-KDHT (Standard); 5α-Dihydro-11-keto testosterone (Standard)	Reference Standards Androgen Receptor	Endocrinology
11-Ketodihydrotestosterone (Standard) is the analytical standard of 11-Ketodihydrotestosterone. This product is intended for research and analytical applications. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells .

HY-181971

XY25028	Orphan Nuclear Receptor Androgen Receptor c-Myc	Cancer
XY25028 is an orally active LRH-1 inhibitor with an IC₅₀ of 0.30 μM. XY25028 inhibits the proliferation of androgen receptor (AR)-positive prostate cancer cells and suppresses the expression of AR target genes KLK2 and KLK3. XY25028 can be used in the research of castration-resistant prostate cancer .

HY-181970

XY25026	Orphan Nuclear Receptor Androgen Receptor c-Myc	Cancer
XY25026 is an orally active LRH-1 inhibitor with an IC₅₀ of 0.28 μM. XY25026 inhibits the proliferation of androgen receptor (AR)-positive prostate cancer cells, suppresses the expression of AR target genes KLK2 and KLK3, and inhibits tumor growth in xenograft models. XY25026 is applicable to the research of castration-resistant prostate cancer .

HY-183667

JNJ-pan-AR	Androgen Receptor Kallikrein	Cancer
JNJ-pan-AR is an orally active androgen receptor (AR) inhibitor with an IC₅₀ of 19 nM and a K_i of 8.4 nM against human wild-type AR. JNJ-pan-AR abolishes androgen-induced *KLK2* and *KLK3* mRNA expression and reduces androgen-dependent colony formation in prostate cancer cells. JNJ-pan-AR blocks AR nuclear translocation, inhibits PSA protein expression, and represses the growth of AR-dependent tumor cells and ARF877L-driven tumor xenografts. JNJ-pan-AR blocks transactivation and signaling of wild-type AR and various mutant AR variants. JNJ-pan-AR is applicable for research on castration-resistant prostate cancer .

HY-RS24126

Klkb1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Klkb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Klkb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Klkb1 Rat Pre-designed siRNA Set A Klkb1 Rat Pre-designed siRNA Set A

HY-RS07388

KLKB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
KLKB1 Human Pre-designed siRNA Set A contains three designed siRNAs for KLKB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

KLKB1 Human Pre-designed siRNA Set A KLKB1 Human Pre-designed siRNA Set A

HY-RS17665

Klkb1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Klkb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klkb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Klkb1 Mouse Pre-designed siRNA Set A Klkb1 Mouse Pre-designed siRNA Set A

Species:	Human (4) Rat (1) Mouse (2) Cynomolgus (1)
Tag:	His (7)
Source:	HEK293 (7) P. pastoris (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700772

	Plasma kallikrein/KLKB1 Protein, Cynomolgus (HEK293, His) Plasma kallikrein; PKK; KLK3; KLKB1; Fletcher factor; Kininogenin	Cynomolgus	HEK293
	Plasma kallikrein (KLKB1) serves as an enzyme, cleaving Lys-Arg and Arg-Ser bonds to release bradykinin from HMW kininogen. It plays a crucial role in the reciprocal activation of factor XII, especially upon binding to a negatively charged surface. Besides its role in the kinin system, KLKB1 may contribute to the renin-angiotensin system by converting prorenin into renin. Plasma kallikrein/KLKB1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Plasma kallikrein/KLKB1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77973A

	Plasma kallikrein/KLKB1 Protein, Mouse (HEK293, His) Plasma kallikrein; PKK; KLK3; KLKB1; Fletcher factor; Kininogenin	Mouse	HEK293
	Plasma kallikrein/KLKB1 enzymatically cleaves Lys-Arg and Arg-Ser bonds, triggering factor XII activation upon binding to a negatively charged surface.It liberates bradykinin from HMW kininogen and is implicated in the renin-angiotensin system, potentially converting prorenin into renin.This underscores the diverse and essential functions of Plasma kallikrein/KLKB1 in various physiological processes.Plasma kallikrein/KLKB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Plasma kallikrein/KLKB1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70249A

	Plasma kallikrein/KLKB1 Protein, Human (HEK293, His) Plasma kallikrein; PKK; KLK3; KLKB1; Fletcher factor; Kininogenin	Human	HEK293
	Plasma kallikrein (KLKB1) serves as an enzyme, cleaving Lys-Arg and Arg-Ser bonds to release bradykinin from HMW kininogen. It plays a crucial role in the reciprocal activation of factor XII, especially upon binding to a negatively charged surface. Besides its role in the kinin system, KLKB1 may contribute to the renin-angiotensin system by converting prorenin into renin. Plasma kallikrein/KLKB1 Protein, Human (HEK293, His) is the recombinant human-derived Plasma kallikrein/KLKB1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77973

	Plasma kallikrein/KLKB1 Protein, Mouse (HEK293, His, solution) Plasma kallikrein; PKK; KLK3; KLKB1; Fletcher factor; Kininogenin	Mouse	HEK293
	Plasma kallikrein/KLKB1 enzymatically cleaves Lys-Arg and Arg-Ser bonds, triggering factor XII activation upon binding to a negatively charged surface.It liberates bradykinin from HMW kininogen and is implicated in the renin-angiotensin system, potentially converting prorenin into renin.This underscores the diverse and essential functions of Plasma kallikrein/KLKB1 in various physiological processes.Plasma kallikrein/KLKB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Plasma kallikrein/KLKB1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71748

	Plasma kallikrein/KLKB1 Protein, Rat (P.pastoris, His) KLKb1; KLK3; PkPlasma kallikrein; EC 3.4.21.34; Fletcher factor; Kininogenin	Rat	P. pastoris
	Plasma kallikrein/KLKB1 enzymatically cleaves Lys-Arg and Arg-Ser bonds, triggering factor XII activation upon binding to a negatively charged surface.It liberates bradykinin from HMW kininogen and is implicated in the renin-angiotensin system, potentially converting prorenin into renin.This highlights the protein's multifaceted role in various physiological processes.Plasma kallikrein/KLKB1 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Plasma kallikrein/KLKB1 protein, expressed by P.pastoris , with N-6*His labeled tag.

HY-P70606A

	Kallikrein-3/PSA Protein, Human (HEK293, His) Prostate-specific antigen; PSA; Gamma-seminoprotein; Kallikrein-3; P-30 antigen; Semenogelase; KLK3; APS	Human	HEK293
	Kallikrein-3 (PSA) protein, pivotal in the male reproductive system, hydrolyzes semenogelin-1, a seminal vesicle protein. This enzymatic activity initiates seminal coagulum liquefaction, crucial for sperm mobility and fertility. PSA's cleavage of semenogelin-1 highlights its importance in the complex processes of semen physiology and male reproductive function. Kallikrein-3/PSA Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-3/PSA protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70249

	Plasma kallikrein/KLKB1 Protein, Human (HEK293, His, solution) rHuPlasma kallikrein/KLKB1, His; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein; KLKB1; KLK3	Human	HEK293
	Plasma kallikrein (KLKB1) serves as an enzyme, cleaving Lys-Arg and Arg-Ser bonds to release bradykinin from HMW kininogen. It plays a crucial role in the reciprocal activation of factor XII, especially upon binding to a negatively charged surface. Besides its role in the kinin system, KLKB1 may contribute to the renin-angiotensin system by converting prorenin into renin. Plasma kallikrein/KLKB1 Protein, Human (HEK293, His, solution) is the recombinant human-derived Plasma kallikrein/KLKB1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70266

	Kallikrein-3/PSA Protein, Human (244a.a, HEK293, His) 1 Publications Verification rHuProstate-specific antigen/KLK3, His; Prostate-Specific Antigen; PSA; Gamma-Seminoprotein; Seminin; Kallikrein-3; P-30 Antigen; Semenogelase; KLK3; APS	Human	HEK293
	Kallikrein-3 (PSA) protein, pivotal in the male reproductive system, hydrolyzes semenogelin-1, a seminal vesicle protein. This enzymatic activity initiates seminal coagulum liquefaction, crucial for sperm mobility and fertility. PSA's cleavage of semenogelin-1 highlights its importance in the complex processes of semen physiology and male reproductive function. Kallikrein-3/PSA Protein, Human (244a.a, HEK293, His) is the recombinant human-derived Kallikrein-3/PSA protein, expressed by HEK293 , with C-His labeled tag.

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Source
Tag
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Gene ID
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Host:	Mouse (3) Rabbit (2)
Reactivity:	Human (5) Rat (1)
Application:	IHC-P (5) IF-Tissue (1) IP (1) WB (2) IHC-F (1) FC (2) ELISA (3)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (3) Monoclonal Antibody (1) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83986

	Prostate Specific Antigen Antibody (YA3683) APS; PSA; hK3; KLK2A1; KLK3	IHC-P, FC, ELISA	Human
	Prostate Specific Antigen Antibody (YA3683) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Prostate Specific Antigen.

HY-P83986A

	Prostate Specific Antigen Antibody (YA3683)(PBS only) APS; PSA; hK3; KLK2A1; KLK3	IHC-P, FC, ELISA	Human
	Prostate Specific Antigen Antibody (YA3683) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Prostate Specific Antigen.

HY-P85338

	Prostate Specific Antigen Antibody (YA5030) KLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase	IHC-P, IHC-F, IF-Tissue, ELISA	Human
	Prostate Specific Antigen Antibody (YA5030) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Prostate Specific Antigen.

HY-P83618

	Plasma Kallikrein Antibody (YA3363) Fletcher factor; kallikrein B plasma; Kallikrein B1; Kininogenin; KLK3; KLKB1; PKK; PKKD; Plasma kallikrein light chain; PPK; Prekallikrein	WB, IHC-P, IP	Human, Rat
	Plasma Kallikrein Antibody (YA3363) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Plasma Kallikrein.

HY-P81792

	Prostate Specific Antigen Antibody (YA1537) KLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase	WB, IHC-P	Human
	Prostate Specific Antigen Antibody (YA1537) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Prostate Specific Antigen.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

KLK3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
KLK3 Human Pre-designed siRNA Set A contains three designed siRNAs for KLK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Klkb1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Klkb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Klkb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

KLKB1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
KLKB1 Human Pre-designed siRNA Set A contains three designed siRNAs for KLKB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Klkb1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Klkb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klkb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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