6 Results for "

LO2 cells

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "LO2 cells" in MCE Product Catalog:

Cat. No.: HY-N10426
CAS No.: 72691-72-6
Target:  

Glycosidase

(+)-Cembrene A (Compound 5) is a α-glucosidase inhibitor with an IC50 of 30.31 μM. (+)-Cembrene A is nontoxic towards human normal hepatocyte (LO2) cells .
loading...
    loading...
Cat. No.: HY-162564
CAS No.: 3034402-33-7
Target:  

Bacterial

Research Areas:  

Infection

Antibacterial agent 221 (compound 3k) is a potent inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 221 shows significant cytotoxicity against human LO2 and HepG2 cells .
loading...
    loading...
Cat. No.: HY-N7161
CAS No.: 466663-11-6
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively .
loading...
    loading...
Cat. No.: HY-146715
CAS No.: 2409479-24-7
Research Areas:  

Cancer

IDO/Tubulin-IN-2 (HT2) is a potent TDO and tubulin inhibitor. IDO/Tubulin-IN-2 also shows potent activity against U87, HepG2, A549, HCT-116, and LO2 cancer cell lines, with IC50 values of 0.43, 0.036, 0.041, 0.095 and 1.04 μM, respectively. IDO/Tubulin-IN-2 remarkably promotes the antitumor activity .
loading...
    loading...
Cat. No.: HY-170606
CAS No.: 3068686-30-3
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-Glucosidase inhibitor with an IC50 of 2.11 μM, which is more potent than existing α-Glucosidase inhibitors such as Acarbose (HY-B0089) (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). α-Glucosidase-IN-79 is non-cytotoxic to human normal hepatocyte (LO2) cells and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research into type 2 diabetes .
loading...
    loading...
Cat. No.: HY-187711
Target:  

FAK

Research Areas:  

Neurological Disease Cancer

FAK-IN-33 is a potent focal adhesion kinase (FAK) inhibitor with an IC50 value of 10.23 nM against FAK. FAK-IN-33 inhibits the viability of U118-MG glioblastoma cells with an IC50 of 0.29 μM, and shows low cytotoxicity toward LO2 and 2BS cells. FAK-IN-33 can be used in studies related to glioblastoma .
loading...
    loading...