22 Results for "

Lipidoid

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "Lipidoid" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-145405
CAS No.: 1220890-25-4
Purity:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
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2
2 Cited Publications
Cat. No.: HY-137500
CAS No.: 2739805-64-0
Purity:  98.43%
NT1-O14B is a tryptamine-derived lipidoid. NT1-O14B incorporates NT-lipidoid into BBB-impermeable lipid nanoparticles (LNPs), enabling the LNPs to cross the BBB. NT1-O14B enhances brain delivery via intravenous injection. NT1-O14B can be used in ischemic stroke research .
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1
1 Cited Publications
Cat. No.: HY-151507
CAS No.: 2322290-93-5
Purity:  ≥98.0%
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
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1
1 Cited Publications
Cat. No.: HY-139298
CAS No.: 1351586-50-9
Purity:  ≥98.0%
Synonyms: Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .
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1
1 Cited Publications
Cat. No.: HY-148859
CAS No.: 2938207-23-7
Purity:  ≥98.0%
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .
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Cat. No.: HY-148488
CAS No.: 2412492-09-0
Purity:  ≥95.0%
A18-Iso5-2DC18 (Compound A18) is a cyclic lipidoid. A18-Iso5-2DC18 partially activates STING. A18-Iso5-2DC18 promotes mRNA protein expression and induces a strong immune response. A18-Iso5-2DC18 can be used in melanoma research .
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Cat. No.: HY-153879
CAS No.: 3067466-15-0
Purity:  ≥99.0%
C12-TLRa is an ionized adjuvant lipid. C12-TLRa targets TLR7/8 receptors in endosomes. C12-TLRa enhances mRNA delivery as a structural component of LNPs. C12-TLRa enhances innate immune responses. C12-TLRa can be used for the research of SARS-CoV-2 mRNA vaccine .
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Cat. No.: HY-W590681
CAS No.: 2803699-72-9
Target:  

Liposome

Research Areas:  

Others

113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
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Cat. No.: HY-W598178
CAS No.: 2227214-78-8
Target:  

Liposome

Research Areas:  

Others

93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
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Cat. No.: HY-137499
CAS No.: 2739805-63-9
Purity:  ≥95.0%
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
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Cat. No.: HY-137501
Purity:  98.04%
Target:  

Liposome

Research Areas:  

Others

306-O12B-3 is a lipidoid that can efficiently deliver ASO both in vitro and in vivo. 306-O12B-3 is used to transport small molecule drugs across the blood-brain barrier (BBB) .
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Cat. No.: HY-160554
CAS No.: 1220890-27-6
Target:  

Liposome

Research Areas:  

Infection Inflammation/Immunology

C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice .
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Cat. No.: HY-172344
CAS No.: 3078748-21-4
Research Areas:  

Others

DB-lipidoid 11-10-8 is an ionizable cationic lipid (pKa = 6.22). DB-lipidoid 11-10-8 can be used in lipid nanoparticle (LNP) studies for in vivo delivery of mRNA .
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Cat. No.: HY-151510
CAS No.: 2412492-19-2
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .
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Cat. No.: HY-W590679
CAS No.: 2566523-07-5
Target:  

Liposome

Research Areas:  

Others

113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
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Cat. No.: HY-159699
CAS No.: 1638334-27-6
Target:  

Liposome

Research Areas:  

Others

80-O18 is a lipidoid that promotes high total cellular uptake with promising delivery capabilities .
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Cat. No.: HY-171953
CAS No.: 3097638-13-3
Target:  

Liposome

Research Areas:  

Others

THP1 Lipid is an ionizable lipidoid. THP1 Lipid can be used to synthesize lipid nanoparticles (LNPs) for delivering mRNA to muscles with minimal toxicity and editing genes in specific liver tissues in tdTomato transgenic mice model. THP1 Lipid can be used for vaccine delivery and CRISPR/Cas9-mediated gene editing research .
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Cat. No.: HY-112773
CAS No.: 1265904-26-4
Purity:  ≥98.0%
1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol] is a lipid/lipidoid used in preparation of lipid-based or lipidoid nanoparticles .
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Cat. No.: HY-171984
CAS No.: 2863553-06-2
Target:  

Liposome

514O6,10 is an ionizable lipidoid containing a branched-tail. 514O6,10 can be used to synthesize lipid nanoparticles (LNPs) for delivering mRNA to natural killer and dendritic cells within the lung. 514O6,10 can be used for the RNA therapies for lung diseases associated with immune cell dysregulation, including cancer, viral infections, and autoimmune disorders research .
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Cat. No.: HY-145797
CAS No.: 1443520-22-6
L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.
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