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Cat. No.: HY-160554

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C12-113

Name: C12-113
Brand: MedChemExpress
SKU: HY-160554
Price: 95.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice.
The product specifications provided below refer solely to the active content of C12-113.

For research use only. We do not sell to patients.

Purity : 98.67%
CAS No.: 1220890-27-6
Formula: C₅₃H₁₁₁N₃O₄
Molecular Weight:854.47

Storage:

Solution, -20°C, 2 years

C12-113 Chemical Structure

CAS No.: 1220890-27-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice^[1]^[2].
The product specifications provided below refer solely to the active content of C12-113.

Chemical Information

CAS No. 1220890-27-6
Appearance Liquid
Molecular Weight 854.47
Formula C₅₃H₁₁₁N₃O₄
Color Colorless to light yellow
SMILES

OC(CCCCCCCCCC)CN(CC(CCCCCCCCCC)O)CCN(CCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years

Solvent & Solubility

In Vitro:

Ethanol : 10 mg/mL (11.70 mM; Need ultrasonic)

View the Complete Stock Solution Preparation Table

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Working solution concentration: 0.22 mg/mL

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li J, Song J S, et al. YY1 regulates melanocyte development and function by cooperating with MITF[J]. PLoS genetics, 2012, 8(5): e1002688. [Content Brief]

Hot Topics

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Topics Lipid Nanoparticles: Key Nucleic Acid Delivery Vectors
Lipid nanoparticles (LNPs) are the most clinically advanced non-viral delivery systems for nucleic acid therapeutics and enable the in vivo delivery of mRNA, siRNA, and other genetic cargos.

2026-06-18

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
Ethanol	1 mM	1.1703 mL	5.8516 mL	11.7032 mL	29.2579 mL
	5 mM	0.2341 mL	1.1703 mL	2.3406 mL	5.8516 mL
	10 mM	0.1170 mL	0.5852 mL	1.1703 mL	2.9258 mL

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