5 Results for "

MCLA

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "MCLA" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-W013275
CAS No.: 128322-44-1
MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
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1
1 Cited Publications
Cat. No.: HY-P99507
CAS No.: 1969309-56-5
Synonyms: MCLA-128; PB4188; R040517

Target:  

EGFR

Research Areas:  

Cancer

Zenocutuzumab (MCLA-128) is a bispecific humanized IgG1 antibody containing two different Fab arms, targeting extracellular domains of HER2 and HER3 .
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Cat. No.: HY-P99406
CAS No.: 2213450-26-9
Synonyms: MCLA 158

Target:  

EGFR

Research Areas:  

Cancer

Petosemtamab (MCLA 158) is an anti- EGFR (Kd: 0.22 nM) and anti-LGR5 (Kd: 0.86 nM) monoclonal antibody (mAb). Petosemtamab leads to EGFR signaling blockade and receptor degradation in LGR5+ cancer cells. Petosemtamab can be used in the research of solid tumors, such as head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer (CRC) .
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Cat. No.: HY-P99390
CAS No.: 2044679-53-8
Synonyms: MCLA 117
Tepoditamab (MCLA-117) is a full-length human IgG1 bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells. Tepoditamab induces upto 30-fold T-cell expansion. Tepoditamab results in moderate to strong cytokine (IFNγ, IL-6, IL-8, IL-10, and TNFα) and IFNγ release in human whole blood and PBMC, respectively. Tepoditamab can be used in acute myeloid leukaemia (AML) research .
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Cat. No.: HY-P990755
CAS No.: 2750004-05-6
Synonyms: MCLA-129

Target:  

EGFR

Research Areas:  

Inflammation/Immunology

Pamvatamig is an anti-EGFR/MET human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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