Pamvatamig
Based on 1 Customer Validation
Pamvatamig is an anti-EGFR/MET human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
For research use only. We do not sell to patients.
- Purity : 98.00%
- CAS No.: 2750004-05-6
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
EGFR & MET
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized EGFR Protein, Human (621a.a, HEK293, His, HY-P70613) can bind Pamvatamig. The EC50 for this effect is 155.7 ng/mL. -
Immobilized HGFR Protein, Human (HEK293, His, HY-P70714) can bind Pamvatamig. The EC50 for this effect is 39.48 ng/mL. -
Flow cytometric analysis of 1X106 Hela cells labeling EGFR with Pamvatamig (HY-P990755, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS No. 2750004-05-6
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Pamvatamig]
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Synonyms
MCLA-129
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Pamvatamig
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)