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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
MELK
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "MELK" in MCE Product Catalog:
24
24
24 Publications Verification
Synonyms: OTS167 hydrochloride
OTSSP167 (OTS167) hydrochloride is a highly potent and ATP-competitive MELK inhibitor with IC50 value of 0.41 nM.
3
3 Cited Publications
Synonyms: NVS-MELK8a hydrochloride
MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.
3
Target:
Research Areas:
MELK-8a (NVS-MELK8a) is a highly potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor with IC50 of 2 nM. MELK-8a also inhibits Flt3 (ITD), Haspin, PDGFRα with IC50s of 0.18, 0.19, and 0.42 μM, respectively. MELK plays an essential role in regulating cell mitosis in a subset of cancer cells .
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
FMF-06-098-1 is a multi-target kinase PROTAC degrader. FMF-06-098-1 can be used to target degradation kinases which degrades AAK1, AΒL2, AURKA, AURKB, BUBIB, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDk6, CDK7, CDK9, CHEK1, CSNKID, EPHA1, PER, FGFR1, GAK, IRAK4, ITK, LIMK2, MAP4K2, MAP4K3, MAPK6, MAPK7, MARK4, MELK, PKN3, PLK4, PRKAA1, PTK2, PTK6, RPS6KA4, S1K2, STK35, TNK2, UHMK1, ULK1, and WEE1 .
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC50 of 10.5 nM. HTH-01-091 also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK and CLK2. HTH-01-091 can be uesd for breast cancer research .
Cat. No.: HY-122665A
Purity: 98.01%
HTH-01-091 TFA is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC50 of 10.5 nM. HTH-01-091 TFA also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK and CLK2. HTH-01-091 TFA can be uesd for breast cancer research .
Cat. No.: HY-RS08328
Target:
Research Areas:
MELK Human Pre-designed siRNA Set A contains three designed siRNAs for MELK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08329
Target:
Research Areas:
Melk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Melk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08330
Target:
Research Areas:
Melk Rat Pre-designed siRNA Set A contains three designed siRNAs for Melk gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-100368AR
CAS No.: 2096992-20-8
Synonyms: NVS-MELK8a hydrochloride (Standard)
Target:
Research Areas:
MELK-8a (hydrochloride) (Standard) is the analytical standard of MELK-8a (hydrochloride) (HY-100368A). This product is intended for research and analytical applications. MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.
Cat. No.: HY-101515R
CAS No.: 2095596-44-2
Target:
Research Areas:
MELK-IN-1 (Standard) is the analytical standard of MELK-IN-1 (HY-101515). This product is intended for research and analytical applications. MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.39 nM, respectively.
Cat. No.: HY-P701811
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MELK; Protein Kinase Eg3; Maternal Embryonic Leucine Zipper Kinase; PEg3 Kinase; KIAA0175; HPK38; Tyrosine-Protein Kinase MELK; Non-Specific Serine/Threonine Protein Kinase; Protein Kinase PK38; HMELK
Species:
Human
Source:
E. coli
Cat. No.: HY-P701810
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MELK; Protein Kinase Eg3; Maternal Embryonic Leucine Zipper Kinase; PEg3 Kinase; KIAA0175; HPK38; Tyrosine-Protein Kinase MELK; Non-Specific Serine/Threonine Protein Kinase; Protein Kinase PK38; HMELK
Species:
Human
Source:
E. coli
Cat. No.: HY-P705043
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MELK; Protein Kinase Eg3; Maternal Embryonic Leucine Zipper Kinase; PEg3 Kinase; KIAA0175; HPK38; Tyrosine-Protein Kinase MELK; Non-Specific Serine/Threonine Protein Kinase; Protein Kinase PK38; HMELK
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
