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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
Mad2
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "Mad2" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: ZIO 301; D 24851
Research Areas:
Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis .
1
1 Cited Publications
Cat. No.: HY-P71540
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HsMad2; Mad 2; Mad2 like 1; Mad2 mitotic arrest deficient like 1; Mad2-like protein 1; Mad2l1; MD2L1_HUMAN; Mitotic arrest deficient 2-like protein 1; Mitotic spindle assembly checkpoint protein Mad2A; REV7
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M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC) .
Cat. No.: HY-RS20566
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Mad2l1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mad2l1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07949
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MAD2L1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-13649R
CAS No.: 204205-90-3
Synonyms: ZIO 301 (Standard); D 24851 (Standard)
Research Areas:
Indibulin (Standard) is the analytical standard of Indibulin. This product is intended for research and analytical applications. Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis .
Cat. No.: HY-123279
CAS No.: 292170-13-9
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Research Areas:
OM137 is an aurora kinase inhibitor, with an IC50 of 21.7 μM (Aurora A kinase) and 2.4 μM (Aurora B kinase). OM137 also inhibits Cdk1/cyclinB and Cdk5/p25 with an approximate IC50 of 20 μM. OM137 reduces spindle checkpoint-signaling proteins (Mad2 and BubR1) at the kinetochores of chromosomes .
Cat. No.: HY-100341R
CAS No.: 312271-03-7
Research Areas:
M2I-1 (Standard) is the analytical standard of M2I-1 (HY-100341). This product is intended for research and analytical applications. M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC) .
Cat. No.: HY-RS07951
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MAD2L2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19788
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Mad2l2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mad2l2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27075
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Mad2l1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mad2l1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07950
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MAD2L1BP Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L1BP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P810361
Synonyms: Homolog of REV7 S cerevisiae, hREV7, Mad2 (mitotic arrest deficient yeast, homolog) like 2, Mad2 homolog, Mad2 like 2, Mad2 mitotic arrest deficient like 2, Mad2-like protein 2, Mad2B, Mad2l2, MD2L2_HUMAN
Cat. No.: HY-RS21382
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Mxi1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mxi1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08864
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MXI1 Human Pre-designed siRNA Set A contains three designed siRNAs for MXI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26284
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Research Areas:
Mad2l2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mad2l2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
