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Multivalent

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By Targets:	ADC Linker (2) Biochemical Assay Reagents (1) Endogenous Metabolite (2) Galectin (2) Glycosidase (4) Liposome (5) Radionuclide-Drug Conjugates (RDCs) (2) Reference Standards (2) TNF Receptor (1) Xanthine Oxidase (2)
By Research Areas:	Cancer (12) Cardiovascular Disease (2) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (2)
Click Chemistry:	Azide (1) Tetrazine (1) Alkynes (2)
Oligonucleotides:	Pegylated Lipids (4) Aptamers (1) Cationic Lipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134418

NOTA	Radionuclide-Drug Conjugates (RDCs)	Cardiovascular Disease Cancer
NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect. NOTA can be used in multiple myeloma, breast cancer, lymphoma and myocardial infarction research .

HY-101779

DCG04	Glycosidase	Others
DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates .

HY-144014

MVL5	Liposome	Cancer
MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA. MVL5 can be used in breast cancer research .

HY-N0814A

Phytic acid dodecasodium hydrate 1 Publications Verification Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate	Xanthine Oxidase Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-159794

Azido-methyltetrazine di-arm linker	ADC Linker	Cancer
Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) .

HY-144312

Thiobis-β-Galactose-propyne	Galectin	Metabolic Disease Cancer
Thiobis-β-Galactose-propyne is an effective multivalent galectin-3 (Gal-3) inhibitor. Galectin-3 is involved in many metabolism processes related to cancer. Galectin-3-IN-1 is a click chemistry reagent. It contains an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules that have an azide group .

HY-172273A

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY	Liposome	Cancer
DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-144313

Galectin-3-IN-2	Galectin	Metabolic Disease Cancer
Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of galectin-3 (Gal-3; IC₅₀=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes .

HY-134418R

NOTA (Standard)	Radionuclide-Drug Conjugates (RDCs) Reference Standards	Cardiovascular Disease Cancer
NOTA (Standard) is the analytical standard of NOTA. This product is intended for research and analytical applications. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect. NOTA can be used in multiple myeloma, breast cancer, lymphoma and myocardial infarction research .

HY-172273

DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY	Liposome	Cancer
DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-N0814B

Phytic acid hexasodium Inositol hexaphosphate hexasodium; SNF472	Xanthine Oxidase Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

HY-172273C

DSPE-PEG3400-M2pep	Liposome	Cancer
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-150723

PBI-6DNJ	Glycosidase	Metabolic Disease
PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a K_i of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research .

HY-177823

C2NP sodium	TNF Receptor	Cancer
C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells.

HY-101779A

DCG04 isomer-1	Glycosidase	Others
DCG04 isomer-1 is an isomer of DCG04 (HY-101779). DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates .

HY-172273B

DSPE-PEG5000-M2pep	Liposome	Cancer
DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-159794A

Azido-methyltetrazine di-arm linker hydrochloride	ADC Linker	Cancer
Azido-methyltetrazine di-arm linker hydrochloride is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) .

HY-N16282

N-Tetamine-pLys40 TFA N,N-Ditetradecylamine-polylysine(40) TFA	Biochemical Assay Reagents	Others
N-Tetamine-pLys40 (N,N-Ditetradecylamine-polylysine(40)) TFA is a multivalent cationic lipid.

HY-101779R

DCG04 (Standard)	Reference Standards Glycosidase	Others
DCG04 (Standard) is the analytical standard of DCG04 (HY-101779). This product is intended for research and analytical applications. DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates .

Cat. No.	Product Name	Type

HY-144014

MVL5	Biochemical Assay Reagents
MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA. MVL5 can be used in breast cancer research .

HY-172273A

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY	Biochemical Assay Reagents
DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-172273

DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY	Biochemical Assay Reagents
DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-172273C

DSPE-PEG3400-M2pep	Biochemical Assay Reagents
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-172273B

DSPE-PEG5000-M2pep	Biochemical Assay Reagents
DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0814A

Phytic acid dodecasodium hydrate 1 Publications Verification Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate	other families Ketones, Aldehydes, Acids Plants Endogenous metabolite Source Classification	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-N0814B

Phytic acid hexasodium Inositol hexaphosphate hexasodium; SNF472	other families Ketones, Aldehydes, Acids Plants Source Classification	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

HY-N16282

N-Tetamine-pLys40 TFA N,N-Ditetradecylamine-polylysine(40) TFA	Lipid	Biochemical Assay Reagents
N-Tetamine-pLys40 (N,N-Ditetradecylamine-polylysine(40)) TFA is a multivalent cationic lipid.

Cat. No.	Product Name		Classification

HY-159794

Azido-methyltetrazine di-arm linker		Azide Tetrazine
Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) .

HY-144312

Thiobis-β-Galactose-propyne		Alkynes
Thiobis-β-Galactose-propyne is an effective multivalent galectin-3 (Gal-3) inhibitor. Galectin-3 is involved in many metabolism processes related to cancer. Galectin-3-IN-1 is a click chemistry reagent. It contains an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules that have an azide group .

HY-144313

Galectin-3-IN-2		Alkynes
Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of galectin-3 (Gal-3; IC₅₀=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes .

Cat. No.	Product Name		Classification

HY-144014

MVL5		Cationic Lipids
MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA. MVL5 can be used in breast cancer research .

HY-172273A

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY		Pegylated Lipids
DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-172273

DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY		Pegylated Lipids
DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-172273C

DSPE-PEG3400-M2pep		Pegylated Lipids
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-177823

C2NP sodium		Aptamers
C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells.

HY-172273B

DSPE-PEG5000-M2pep		Pegylated Lipids
DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

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Multivalent

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Click Chemistry

Oligonucleotides

Natural
Products