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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Multivalent
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Multivalent" in MCE Product Catalog:
1
1 Cited Publications
Art. -Nr.: HY-N0814A
CAS. Nr.: 123408-98-0
Synonyms: Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate
Forschungsgebiete:
NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect. NOTA can be used in multiple myeloma, breast cancer, lymphoma and myocardial infarction research .
Art. -Nr.: HY-159794
CAS. Nr.: 2861998-16-3
Target:
Forschungsgebiete:
Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) .
Target:
Forschungsgebiete:
Thiobis-β-Galactose-propyne is an effective multivalent galectin-3 (Gal-3) inhibitor. Galectin-3 is involved in many metabolism processes related to cancer. Galectin-3-IN-1 is a click chemistry reagent. It contains an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules that have an azide group .
Art. -Nr.: HY-W008425
CAS. Nr.: 10160-24-4
Synonyms: 7-Bromoheptan-1-ol
Forschungsgebiete:
7-Bromo-1-heptanol (7-Bromoheptan-1-ol) acts as a HaloTag-GPSM2 inhibitor and an organic synthesis intermediate. It forms a covalent irreversible bond with HaloTag-GPSM2, thereby blocking the subsequent labeling effect of fluorescent HaloTag ligands and enabling pulse-chase analysis of protein turnover. 7-Bromo-1-heptanol can be used to synthesize PROTAC BET degraders and multivalent glycoporphyrin antiviral compounds. It is applicable to cancer-related research .
Art. -Nr.: HY-172273A
DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
Art. -Nr.: HY-144313
CAS. Nr.: 2883648-71-1
Target:
Forschungsgebiete:
Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of galectin-3 (Gal-3; IC50=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes .
Art. -Nr.: HY-134418R
CAS. Nr.: 56491-86-2
Forschungsgebiete:
NOTA (Standard) is the analytical standard of NOTA. This product is intended for research and analytical applications. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect. NOTA can be used in multiple myeloma, breast cancer, lymphoma and myocardial infarction research .
Art. -Nr.: HY-172273
DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
Art. -Nr.: HY-N0814B
CAS. Nr.: 34367-89-0
Synonyms: Inositol hexaphosphate hexasodium; SNF472
Art. -Nr.: HY-172273C
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
Art. -Nr.: HY-177823
Target:
Forschungsgebiete:
C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells.
Art. -Nr.: HY-101779A
Target:
Forschungsgebiete:
DCG04 isomer-1 is an isomer of DCG04 (HY-101779). DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates .
Art. -Nr.: HY-150723
CAS. Nr.: 2857098-72-5
Target:
Forschungsgebiete:
PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a Ki of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research .
Art. -Nr.: HY-172273B
DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
Art. -Nr.: HY-159794A
Target:
Forschungsgebiete:
Azido-methyltetrazine di-arm linker hydrochloride is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) .
Art. -Nr.: HY-N16282
Synonyms: N,N-Ditetradecylamine-polylysine(40) TFA
Target:
Forschungsgebiete:
N-Tetamine-pLys40 (N,N-Ditetradecylamine-polylysine(40)) TFA is a multivalent cationic lipid.
Art. -Nr.: HY-NP229
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
