36 Results for "

N-formyl

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "N-formyl" in MCE Product Catalog:

17
17 Publications Verification
Cat. No.: HY-P0224
CAS No.: 59880-97-6
Synonyms: fMLP; N-formyl-MLF
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.
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2
2 Cited Publications
Cat. No.: HY-103286
CAS No.: 204067-01-6
Purity:  99.38%
Target:  

Bombesin Receptor

Research Areas:  

Cancer

PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells.
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2
2 Cited Publications
Cat. No.: HY-P1795
CAS No.: 148182-34-7
Research Areas:  

Inflammation/Immunology

Boc-dPhe-Leu-dPhe-Leu-Phe (Boc-fLfLF) is a selective N-formyl peptide receptor1 (FPR1) antagonist. Boc-dPhe-Leu-dPhe-Leu-Phe inhibits fMIFL(HY-P0224)-induced NADPH oxidase activity. Boc-dPhe-Leu-dPhe-Leu-Phe can be used for the study of inflammation .
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1
1 Cited Publications
Cat. No.: HY-N2071
CAS No.: 77-53-2
Synonyms: (+)-Cedrol; α-Cedrol
Cedrol is a potent competitive inhibitor of cytochrome P-450(CYP) enzyme. Cedrol plays an anticancer role by inducing cell cycle arrest and Caspase-dependent apoptosis. Cedrol acts as a neutrophil agonist that can desensitize cells to subsequent stimulation of N-formyl peptides. Cedrol prevents neuropathic pain caused by chronic contractile injury by inhibiting oxidative stress and inflammation. In addition, Cedrol has antibacterial, hair loss prevention and anti-anxiety properties .
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Cat. No.: HY-N2100
CAS No.: 115713-06-9
6'-O-beta-D-Glucosylgentiopicroside is a secoiridoid isolated from the roots of G. straminea. 6'-O-beta-D-Glucosylgentiopicroside strongly suppresses N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation .
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Cat. No.: HY-P10738
CAS No.: 863418-59-1
Research Areas:  

Infection

N-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF can inhibit the FPR-1-mediated chemotactic response of polymorphonuclear leukocytes (PMNs) to bacterial peptides .
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Cat. No.: HY-128113
CAS No.: 356776-32-4
Purity:  99.48%
Research Areas:  

Inflammation/Immunology

AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense .
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Cat. No.: HY-P1744
CAS No.: 67247-11-4
Synonyms: fMLFK
Research Areas:  

Inflammation/Immunology

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D281 7.32G, respectively .
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Cat. No.: HY-135108
CAS No.: 126088-82-2
Purity:  98.15%
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

QWF Peptide is a substance P (SP) antagonist. QWF Peptide inhibits SP-induced biological responses and also suppresses SP-induced contraction of isolated guinea pig tracheal strips. QWF Peptide can be used for asthma-related research .
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Cat. No.: HY-P1121A
CAS No.: 1435781-74-0
Research Areas:  

Inflammation/Immunology

WKYMVM-NH2 TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase .
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Cat. No.: HY-P3318
CAS No.: 73572-58-4
Synonyms: L-BOC2
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) is a N-formyl peptide receptors (FPR) inhibitor. Boc-Phe-Leu-Phe-Leu-Phe abolishes the FMLP-induced release of peptide leukotrienes. Boc-Phe-Leu-Phe-Leu-Phe inhibits the sprouting of human umbilical vein endothelial cell (HUVEC) spheroids mediated by proliferative diabetic retinopathy (PDR) vitreous and vascular endothelial growth factor (VEGF) respectively in a three-dimensional fibrin gel. Boc-Phe-Leu-Phe-Leu-Phe inhibits the anti-inflammatory and antifibrotic effects of Ac2-26 (HY-P1098). Boc-Phe-Leu-Phe-Leu-Phe can be used for the study of immunology .
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Cat. No.: HY-P1591
CAS No.: 71901-21-8
Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH
Research Areas:  

Inflammation/Immunology

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist .
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Cat. No.: HY-P1756
CAS No.: 17351-32-5
Research Areas:  

Inflammation/Immunology

N-Formyl-Met-Ala-Ser is a peptide, binds to formyl peptide receptors on neutrophils.
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Cat. No.: HY-120571
CAS No.: 127481-29-2
Purity:  99.54%
Research Areas:  

Cancer

L-674573 is a quinoline leukotriene synthesis inhibitor, inhibiting Calcimycin (HY-N6687)- and N-Formyl-Met-Leu-Phe (HY-P0224)-induced leukotriene production with IC50s of 100 nM and 50 nM, respectively. L-674573 selectively inhibits Calcimycin- and N-Formyl-Met-Leu-Phe-induced 5-lipoxygenase translocation .
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Cat. No.: HY-151454S
N-Formyl palbociclib-d8 is the deuterium-labeled N-Formyl palbociclib.
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Cat. No.: HY-134149
CAS No.: 117810-61-4
Research Areas:  

Others

N-Formyl Desloratadine is a biological molecule.
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Cat. No.: HY-I0591
CAS No.: 6113-61-7
Synonyms: N-formyl-S-leucine; N-formylleucine; NSC 334321
Research Areas:  

Others

N-Formyl-L-leucine is a leucine derivative .
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Cat. No.: HY-P10738A
Research Areas:  

Infection

N-Formyl-MMYALF TFA is a mitochondrial N-formyl peptide that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF TFA can inhibit the FPR-1-mediated chemotactic response of PMNs to bacterial peptides .
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Cat. No.: HY-W142169
CAS No.: 15191-21-6
Synonyms: formyl-L-histidine
Research Areas:  

Others

N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a Ki value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a Ki value of 4.26 mM .
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Cat. No.: HY-W125431
CAS No.: 92700-82-8
Synonyms: N-formyl Trimetazidine
Target:  

Drug Intermediate

Research Areas:  

Others

Trimetazidine impurity 9 (N-Formyl Trimetazidine) is an impurity of Trimetazidine.
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