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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
NCL
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "NCL" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P71760
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C23; FLJ45706; MS1116 ; NCL; Nucl; Nucleolin; Protein C23
Species:
Source:
Cat. No.: HY-174346
CAS No.: 3118494-67-7
Research Areas:
Skp2-IN-4 is an Skp2 inhibitor with a IC50 of 0.38 μM for Skp2-Cks1 binding. Skp2-IN-4 improves anti-tumor activity, inhibits the proliferation and induces S phase arrest by targeting Skp2. Skp2-IN-4 significantly enhances Cisplatin (HY-17394) chemosensitivity by suppressing the tumor cell stemness in NCl-H1299 xenograft mice model, promising for lung cancer and esophageal cancer research .
Cat. No.: HY-12645
CAS No.: 1196119-03-5
Target:
Research Areas:
NCL1 is a phenylcyclopropylamine (PCPA)-based Lysine-specific demethylase 1 (LSD1) inhibitor. NCL1 selectively inhibits LSD1 in preference to LSD2, with IC50 values of 2.5 and 26 μM for LSD1 and LSD2, respectively .
Cat. No.: HY-178048
CAS No.: 3086460-35-4
Target:
Research Areas:
Neuroprotective agent 13 is a brain-penetrant 1H-benzo[d]imidazoles compound with neuroprotective effect. Neuroprotective agent 13 can activate autophagy and clear SCMAS accumulation from iPSC-derived neural progenitor cells. Neuroprotective agent 13 can be used for the research of neurological disease, such as neuronal ceroid lipofuscinoses (NCLs) .
Cat. No.: HY-RS09086
Target:
Research Areas:
NCL Human Pre-designed siRNA Set A contains three designed siRNAs for NCL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17936
Target:
Research Areas:
Ncl Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ncl gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P5551
Target:
Research Areas:
Cat. No.: HY-178052
CAS No.: 3086460-57-0
Target:
Research Areas:
Neuroprotective agent 14 is a brain-penetrant 1H-benzo[d]imidazoles compound with neuroprotective effect. Neuroprotective agent 14 can activate autophagy and clear SCMAS accumulation from iPSC-derived neural progenitor cells. Neuroprotective agent 14 can be used for the research of neurological disease, such as neuronal ceroid lipofuscinoses (NCLs) .
Cat. No.: HY-RS03886
Target:
Research Areas:
DNAJC5 Human Pre-designed siRNA Set A contains three designed siRNAs for DNAJC5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24407
Target:
Research Areas:
Ncl Rat Pre-designed siRNA Set A contains three designed siRNAs for Ncl gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704808
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C23; FLJ45706; MS1116 ; NCL; Nucl; Nucleolin; Protein C23
Cat. No.: HY-185723
Target:
Research Areas:
rG4 WT_AHPC_PEG2 is a selective RNA G-quadruplex-based DHX36 PROTAC degrader with a Kd value of 79.7 nM. rG4 WT_AHPC_PEG2 degrades DHX36 via a proteasome-dependent mechanism, without significantly degrading other G4-binding proteins including NCL, DHX9, hnRNP, SRSF and FMR1 .
Cat. No.: HY-P704081
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C23; FLJ45706; MS1116 ; NCL; Nucl; Nucleolin; Protein C23
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
