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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
NK3R
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "NK3R" in MCE Product Catalog:
5
Target:
Research Areas:
Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes.
3
3 Cited Publications
Synonyms: MLE-4901; AZD2624; AZD4901
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Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist.
Cat. No.: HY-P0242
CAS No.: 86933-75-7
Cat. No.: HY-P0242A
CAS No.: 101536-55-4
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
Cat. No.: HY-P3862
CAS No.: 110880-53-0
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Cat. No.: HY-181682
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Research Areas:
NK3R antagonist-1 is an orally active neurokinin-3 receptor (NK3R) antagonist with an IC50 of 53.61 nM. NK3R antagonist-1 reduces plasma luteinizing hormone (LH) levels in ovariectomized rat models. NK3R antagonist-1 is applicable to research related to menopausal hot flushes .
Cat. No.: HY-184769
CAS No.: 909856-46-8
Research Areas:
NK3R antagonist-2 (Compound 45) is a small-molecule antagonist of tachykinin NK3R, with an IC50 of 1100 nM and a Ki of 1800 nM. NK3R antagonist-2 can be used in the research of schizophrenia .
Cat. No.: HY-176546
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NK3R-IN-2 is an orally active NK3R inhibitor with an IC50 of 330.50 nM for human NK3R. NK3R-IN-2 can pass through the blood-brain barrier. NK3R-IN-2 has excellent NK3R binding affinity (IC50 = 87.31 nM) in CHO-K1 cells. NK3R-IN-2 effectively inhibits the level of luteinizing hormone (LH). NK3R-IN-2 can be used for research on hormone related conditions .
Cat. No.: HY-149358
CAS No.: 2854331-14-7
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NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model .
Cat. No.: HY-177079S
CAS No.: 2759134-55-7
Cat. No.: HY-14432R
CAS No.: 941690-55-7
Synonyms: MLE-4901 (Standard); AZD2624 (Standard); AZD4901 (Standard)
Research Areas:
Pavinetant (Standard) is the analytical standard of Pavinetant. This product is intended for research and analytical applications. Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist.
Cat. No.: HY-122286
CAS No.: 272104-60-6
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SB 414240 is a selective neurokinin-2 receptor (NK-2R) antagonist with Kis of 1 nM and 193 nM for human NK-3R and human NK-2R, respectively. SB 414240 does not bind the human μ-opioid receptor (hMOR). SB 414240 can be used for the study of neurological disease .
Cat. No.: HY-RS14149
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TACR3 Human Pre-designed siRNA Set A contains three designed siRNAs for TACR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14150
Target:
Research Areas:
Tacr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tacr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
