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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
Nuclear factor-kappa B (NF-
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "Nuclear factor-kappa B (NF-" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P81238
Synonyms: Phospho-NF-KB p65 (Ser536) ;
NF-kB p65 (phospho S536); p-NF-κB p65(Phospho-Ser536); RELA(phospho S536); NF kB P65; NF-kB p65; NFKBp65; NF-κBp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (Nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)); V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A; p65NFKB; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NFKB 3; NFKB3; Nuclear factor NF kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear factor Of kappa Light Polypeptide Gene Enhancer In B Cells; TF65_HUMAN. NFκB-p65; NFκB p65; NF κB-p65; NFκBp65;
3
Target:
Research Areas:
3
Category:
Infection Colophony Pinaceae Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields Inflammation/Immunology
Target:
3
3 Cited Publications
Cat. No.: HY-P9958A
CAS No.: 615258-40-7
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P73681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RELA; NF-kappa-B Transcription factor P65; Prev. NFKB3; P65 Iso5 Isoform Delta 10; Nuclear factor Of kappa Light Polypeptide Gene Enhancer In B-Cells 3; Alternative Protein RELA; P65; NF-kappa-B P65delta3; V-Rel Avian Reticuloendotheliosis Viral Oncogene
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
2
1
Research Areas:
Flumethasone (Flumetasone) is an orally active, high selective and potent glucocorticoid receptor (GR) agonist. Flumethasone activates GR to inhibit nuclear factor kappa B (NF-κB)-mediated pro-inflammatory cytokine production (TNF-α, IL-1β) and promotes anti-inflammatory gene expression (IL-10), while also regulating metabolic enzyme activity (tyrosine aminotransferase induction). Flumethasone is promising for research of inflammatory diseases, cancer, and endocrine regulation .
Cat. No.: HY-N2056
CAS No.: 17019-92-0
Synonyms: 11-Keto-β-boswellic acid
Category:
Triterpenes Terpenoids Boswellia serrata Plants Burseraceae Disease Research Fields Cancer
Target:
Cat. No.: HY-N2106
CAS No.: 67909-49-3
Category:
Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Inflammation/Immunology Indole Alkaloids
Target:
Cat. No.: HY-175703
CAS No.: 3108878-05-0
Research Areas:
RANKL-IN-1 is a selective and orally active Receptor Activator of Nuclear Factor-κ B Ligand (RANKL) inhibitor with a KD value of 7.6 μM. RANKL-IN-1 exhibits inhibitory activity and selectivity against osteoclastogenesis with an IC50 value of 0.07 μM and SI of 82.57. RANKL-IN-1binds directly to RANKL and blocks the RANKL-induced activation of the NF-κB and MAPK pathways. RANKL-IN-1 can be used for the research of metabolic disease, such as osteoporosis .
Cat. No.: HY-N0632R
CAS No.: 65497-07-6
Target:
Cat. No.: HY-149838
CAS No.: 3033815-24-3
NF-κB-IN-9 is a nuclear factor kappa B (NF-κB) targeting sonosensitizer (λex/λem=489/628 nm). NF-κB-IN-9 exhibits strong inhibition on NF-κB signaling due to its two resveratrol units in one molecule. NF-κB-IN-9 has anti-tumor activity and shows remarkable sonocytotoxicity against cancer cells. NF-κB-IN-9 has biosafety in eenograft mice model.
Cat. No.: HY-139833
Research Areas:
Anti-inflammatory agent 6 blocks the phosphorylation of I kappa b kinase α/β (IKKα/β), IκBα, and nuclear factor kB p65 (NF-κB p65) which is a key controller of inflammation, thereby showing anti-inflammatory potential.
Cat. No.: HY-N2106R
CAS No.: 67909-49-3
Cat. No.: HY-N2056R
CAS No.: 17019-92-0
Synonyms: 11-Keto-β-boswellic acid (Standard)
Category:
Cat. No.: HY-P85639
Synonyms: DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappaB; NF kappabeta; NF kB1; NFkappaB; NFKB 1; NFKB p105; NFKB p50; Nfkb1; NFKB1_HUMAN; Nuclear factor kappa B DNA binding subunit; Nuclear factor kappa-B, subunit 1; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p105; p50; p84/NF-kappa-B1 p98.
Cat. No.: HY-P71124
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NFKB1; KBF1; Nuclear factor kappa B Subunit 1; P105; Nuclear factor Of kappa Light Polypeptide Gene Enhancer In B-Cells 1; P50; Nuclear factor NF-kappa-B P105 Subunit; Nuclear factor kappa-B DNA Binding Subunit; DNA-Binding factor KBF1; Nuclear factor NF-
Species:
Human
Source:
E. coli
Cat. No.: HY-P81049
Synonyms: NFKB1; NF-KB; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Nuclear factor NF-kappa-B p50 subunit; NFkB p105 / p50; NFkB p105/p50; Nuclear factor kappa B subunit 1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta;
Cat. No.: HY-P702972
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: NFKB2; H2TF1; Nuclear factor kappa B Subunit 2; LYT10; Nuclear factor NF-kappa-B P100 Subunit; P105; DNA-Binding factor KBF2; Nuclear factor Of kappa Light Chain Gene Enhancer In B Cells 2; P49/P100; Nuclear factor NF-kappa-B P52 Subunit; LYT-10; Nuclear
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
