1471 Results for "

Nystatin A-1

" in MedChemExpress (MCE) Product Catalog:
Products (1471)

1471 Results for "Nystatin A-1" in MCE Product Catalog:

909
909 Publications Verification
Cat. No.: HY-100558
CAS No.: 88899-55-2
Purity:  99.95%
Synonyms: BafA1
Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H +-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis [1] .
loading...
    loading...
59
59 Cited Publications
Cat. No.: HY-17409
CAS No.: 1400-61-9
Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion [1] . Nystatin is a cholesterol-sequestering agent , partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis .
loading...
    loading...
29
29 Cited Publications
Cat. No.: HY-N7452
CAS No.: 4434-05-3
Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1 shows anti-orthopoxvirus activity.
loading...
    loading...
22
22 Cited Publications
Cat. No.: HY-A0181A
CAS No.: 18422-05-4
Synonyms: 5'-AMP monohydrate
Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2 [1] .
loading...
    loading...
22
22 Cited Publications
Cat. No.: HY-A0181
CAS No.: 61-19-8
Synonyms: AMP
Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [1] .
loading...
    loading...
22
22 Cited Publications
Cat. No.: HY-107738
CAS No.: 95975-55-6
Purity:  99.81%
Synonyms: Z/E-Guggulsterone
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt [1] . Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC50s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively .
loading...
    loading...
18
18 Cited Publications
Cat. No.: HY-19533
CAS No.: 160098-96-4
Target:  

Adenosine Receptor

Research Areas:  

Cancer

SCH 58261 is a potent, selective and competitive antagonist of adenosine A2A receptor with an IC50 of 15 nM, and displays 323-, 53- and 100-fold more selective for A2A receptor than A1, A2B, and A3 receptors, respectively [1] .
loading...
    loading...
18
18 Cited Publications
Cat. No.: HY-B0228
CAS No.: 58-61-7
Synonyms: Adenine riboside; D-Adenosine
Adenosine (Adenine riboside), a ubiquitous and BBB-permeable endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation [1] .
loading...
    loading...
16
16 Cited Publications
Cat. No.: HY-N0092
CAS No.: 58-63-9
Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors [1] .
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-B0140
CAS No.: 317-34-0
Aminophylline is a competitive phosphodiesterase 3/4 (PDE3/4) inhibitor. Aminophylline also acts as an adenosine receptor antagonist. Aminophylline elevates intracellular cAMP levels via competitive inhibition of PDE3 and PDE4, antagonizes adenosine A1 receptor (ADORA1), regulates intracellular calcium signaling and synaptic vesicle cycling, upregulates the PPAR signaling pathway, and downregulates glutamatergic synaptic pathways simultaneously. Aminophylline can be used in research related to major depressive disorder, epilepsy, asthma, and chronic obstructive pulmonary disease (COPD) [1] .
loading...
    loading...
10
10 Cited Publications
Cat. No.: HY-131614
CAS No.: 136186-07-7
Purity:  99.86%
Target:  

Calcium Channel

Research Areas:  

Others

TPC2-A1-N is a powerful and Ca 2+-permeable agonist of two pore channel 2 (TPC2), which plays its role by mimicking the physiological actions of NAADP. TPC2-A1-P reproducibly evokes significant Ca 2+ responses from TPC2 (EC50=7.8 μM), and the effect can be blocked by several TPC blockers. TPC2-A1-N can be used to probe different functions of TPC2 channels in intact cells [1] .
loading...
    loading...
10
10 Cited Publications
Cat. No.: HY-14917
CAS No.: 544417-40-5
Purity:  99.62%
Synonyms: BAY 68-4986
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease

Capadenoson is a selective agonist of adenosine-A1 receptor.
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-100937
CAS No.: 102146-07-6
Purity:  99.96%
Synonyms: PD 116948
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease

DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective Adenosine A1 receptor antagonist, with a Ki of 0.46 nM in 3H-CHA binding to A1 receptors in rat whole brain membranes [1] .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-14121
CAS No.: 264622-58-4
Purity:  98.31%
MRS 1754 is a selective antagonist radioligand for A2B adenosine receptor with very low affinity for A1 and A3 receptors of both humans and rats [1].
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-103171
CAS No.: 910487-58-0
Purity:  99.93%
BAY 60-6583 is a potent and high-affinity agonist of adenosine A2B receptor (EC50=3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with Ki values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model [1] .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-P81227
Synonyms: Collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen type I alpha 1; Collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat, Rabbit

loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-131615
CAS No.: 2804595-86-4
Purity:  99.79%
Target:  

Sodium Channel

Research Areas:  

Others

TPC2-A1-P is a powerful and membrane permeable agonist of two pore channel 2 (TPC2) with an EC50 of 10.5 μM. TPC2-A1-P plays its role by mimicking the physiological actions of PI(3,5)P2. TPC2-A1-P also shows higher potency to induce Na 2+ mobilisation from TPC2 than TPC-A1-N (HY-131614). TPC2-A1-P can be used to probe different functions of TPC2 channels in intact cells [1] .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-B0478
CAS No.: 25332-39-2
Synonyms: AF-1161
Trazodone hydrochloride (AF-1161) is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). Trazodone hydrochloride has anti-depressant and anti-insomnious activity. Trazodone hydrochloride exerts antagonistic properties against a1- and a2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects [1].
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-B0478A
CAS No.: 19794-93-5
Synonyms: AF-1161 free base
Trazodone (AF-1161 free base) is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). Trazodone has anti-depressant and anti-insomnious activity. Trazodone exerts antagonistic properties against a1- and a2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects [1].
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-P700261
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRL; PPRL; Prolactin; GHA1; Luteotropic Hormone; Decidual Prolactin; Prolactin Peptide; Growth Hormone A1; Luteotropin
Species:  
Mouse
Source:  
E. coli
loading...
    loading...