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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
P47
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "P47" in MCE Product Catalog:
44
44 Publications Verification
Synonyms: GF109203X; Go 6850
Research Areas:
Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I is also a GSK-3 inhibitor .
44
44 Publications Verification
Synonyms: GF109203X hydrochloride; Go 6850 hydrochloride
Research Areas:
Bisindolylmaleimide I (GF109203X) hydrochloride is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I hydrochloride is also a GSK-3 inhibitor .
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1 Cited Publications
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DATPT is a 12WLVSKF17 peptide-mimetic molecule. DATPT blocks the SNX9-p47phox interaction in the endosome and suppresses reactive oxygen species and inflammatory cytokine production. DATPT with anti-inflammatory and antibacterial functions has the potential for the research of sepsis .
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NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 diTFA inhibits ROS production derived from NOX2 in cells .
Cat. No.: HY-13867R
CAS No.: 133052-90-1
Synonyms: GF109203X (Standard); Go 6850 (Standard)
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Research Areas:
Bisindolylmaleimide I (Standard) is the analytical standard of Bisindolylmaleimide I. This product is intended for research and analytical applications. Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I is also a GSK-3 inhibitor .
Cat. No.: HY-156425
CAS No.: 2648709-79-7
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NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells .
Cat. No.: HY-RS20305
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Ncf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ncf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P83418A
Synonyms: P47; Platelet 47 kDa protein
Cat. No.: HY-RS10677
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PLEK Human Pre-designed siRNA Set A contains three designed siRNAs for PLEK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27052
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Ddx39b Rat Pre-designed siRNA Set A contains three designed siRNAs for Ddx39b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02780
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Research Areas:
CLEC11A Human Pre-designed siRNA Set A contains three designed siRNAs for CLEC11A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-13867AR
CAS No.: 176504-36-2
Synonyms: GF109203X hydrochloride (Standard); Go 6850 hydrochloride (Standard)
Target:
Research Areas:
Bisindolylmaleimide I (hydrochloride) (Standard) is the analytical standard of Bisindolylmaleimide I (hydrochloride). This product is intended for research and analytical applications. Bisindolylmaleimide I (GF109203X) hydrochloride is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I hydrochloride is also a GSK-3 inhibitor .
Cat. No.: HY-RS09592
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Research Areas:
NSFL1C Human Pre-designed siRNA Set A contains three designed siRNAs for NSFL1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06807
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ING1 Human Pre-designed siRNA Set A contains three designed siRNAs for ING1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00516
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Research Areas:
AKAP13 Human Pre-designed siRNA Set A contains three designed siRNAs for AKAP13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
