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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
63 Results for "
PARK
" in MedChemExpress (MCE) Product Catalog:
Products (63)
63 Results for "PARK" in MCE Product Catalog:
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Cat. No.: HY-163562
CAS No.: 3117543-49-1
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JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research .
Cat. No.: HY-163563
CAS No.: 3117543-57-1
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JYQ-173, a chemical probe, is a selective inhibitor for human Parkinson disease protein 7 (PARK7), with an IC50 of 19 nM. JYQ-173 exhibits good cell permeability. JYQ-173 is the ligand for target protein PARK7, which can be utilized for synthesis of PROTAC Degrader JYQ-194 (HY-163564) .
Cat. No.: HY-RS10043
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PARK7 Human Pre-designed siRNA Set A contains three designed siRNAs for PARK7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-163564
CAS No.: 3117543-71-9
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Research Areas:
JYQ-194 is a PROTAC degrader that selectively induces PARK7 degradation by recruiting cereblon. JYQ-194 induces proteasome-dependent degradation of PARK7 in human tumor cells. JYQ-194 is applicable to research related to Parkinson's disease and cancer .
Cat. No.: HY-RS17611
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Park7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Park7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24071
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Park7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Park7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P10367
CAS No.: 518069-98-2
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Cat. No.: HY-RS25456
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Research Areas:
Prkn Rat Pre-designed siRNA Set A contains three designed siRNAs for Prkn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-19156A
CAS No.: 138620-17-4
Synonyms: ICI-D 6888 hydrochloride
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ZD-6888 hydrochloride (ICI-D 6888 hydrochloride) is an antagonist for angiotensin II, which competitively inhibits the angiotensin II-mediated release of renin, affects the renal structure and function .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
