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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
PBG
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "PBG" in MCE Product Catalog:
1
Target:
Research Areas:
Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran can be used for the research of acute hepatic porphyria (AHP) .
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1 Cited Publications
Synonyms: ALN-AS1 sodium
Target:
Research Areas:
Givosiran (ALN-AS1) sodium is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran sodium downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran sodium demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran sodium can be used for the research of acute hepatic porphyria (AHP) .
Synonyms: N-Phenylbiguanide; PBG; 1-Phenylbiguanide
Target:
Research Areas:
Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
Synonyms: N-Phenylbiguanide hydrochloride; PBG hydrochloride; 1-Phenylbiguanide hydrochloride
Target:
Research Areas:
Phenylbiguanide hydrochloride is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
Cat. No.: HY-101331R
CAS No.: 102-02-3
Synonyms: N-Phenylbiguanide (Standard); PBG (Standard); 1-Phenylbiguanide (Standard)
Target:
Research Areas:
Phenylbiguanide (Standard) is the analytical standard of Phenylbiguanide. This product is intended for research and analytical applications. Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
Cat. No.: HY-P70269A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Porphobilinogen deaminase; PBG-D; Hydroxymethylbilane synthase (HMBS); Pre-uroporphyrinogen synthase
Cat. No.: HY-P70269Y
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuPorphobilinogen deaminase/HMBS, His; Porphobilinogen Deaminase; PBG-D; Hydroxymethylbilane Synthase; HMBS; Pre-Uroporphyrinogen Synthase; HMBS; PBGD; UPS
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
