Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
PTP4A2
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "PTP4A2" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
JMS-053 is an efficient and reversible PTP4A3 inhibitor, with an IC50 value of 18 nM.
JMS-053 demonstrates broad PTP4A inhibitory activity with IC50s of 50 nM and 53 nM for PTP4A1 and PTP4A2, respectively. JMS-053 exhibits IC50 values of 92.6 nM and 207.6 nM for CDC25B and DUSP3, respectively. JMS-053 can effectively inhibit the activity of PTP4A3, inhibit tumor cell proliferation and migration through multiple mechanisms such as interfering with RhoA and STAT3/p38 signaling pathway. JMS-053 can be used for the study of cancers such as ovarian cancer, breast cancer and colon cancer .
Cat. No.: HY-RS11410
Target:
Research Areas:
PTP4A2 Human Pre-designed siRNA Set A contains three designed siRNAs for PTP4A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26696
Target:
Research Areas:
Ptp4a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptp4a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20192
Target:
Research Areas:
Ptp4a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptp4a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P83448A
Synonyms: protein tyrosine phosphatase type IVA; member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; PTP-IV1a; PTP-IV1b
Cat. No.: HY-183953
CAS No.: 86126-60-5
Target:
Research Areas:
JMS-038 is a PTP4A3 inhibitor with an IC50 of 0.018 μM against human PTP4A3. JMS-038 can be used in ovarian cancer-related research .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
