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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Plasmodium falciparum W2
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Plasmodium falciparum W2" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N6009
CAS No.: 33390-41-9
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage .
Cat. No.: HY-186055
CAS No.: 1258387-05-1
Antimalarial agent 58 is a diaminoquinoline methanol compound with weak in vitro activity against Plasmodium falciparum strain D6, and no activity against Plasmodium falciparum strains W2, C235 and C2A .
Cat. No.: HY-N11031
CAS No.: 111479-04-0
Target:
Cat. No.: HY-120104
CAS No.: 171674-89-8
Synonyms: (±)-Nitidanin
Cat. No.: HY-181864
CAS No.: 2310304-72-2
Rac1-IN-6 (Compound 5e) is a selective Rac1 inhibitor and antimalarial agent. Rac1-IN-6 inhibits Rac1 activation induced by the Escherichia coli CNF1 toxin. Rac1-IN-6 suppresses the growth of chloroquine-sensitive Plasmodium falciparum D10 (IC50 = 76.0 nM) and chloroquine-resistant Plasmodium falciparum W2 (IC50 = 236.6 nM) .
Cat. No.: HY-183009
Target:
Research Areas:
Pf20S-IN-1 is a selective inhibitor of the 20S proteasome β5 subunit of Plasmodium falciparum. Pf20S-IN-1 exhibits antiparasitic activity against Plasmodium falciparum, with an EC50 of 20.1 nM against the Plasmodium falciparum W2 strain. Pf20S-IN-1 shows weak inhibitory effect on human 20S proteasome, has no obvious toxicity to human foreskin fibroblasts (HFF), and has a selectivity index > 25000. Pf20S-IN-1 can be used in malaria research .
Cat. No.: HY-N21530
CAS No.: 1295650-67-7
Cat. No.: HY-N10667A
CAS No.: 77790-52-4
Synonyms: (+)-Glaberide I
Target:
Cat. No.: HY-N18179
CAS No.: 15575-49-2
Category:
Alkaloids Rutaceae Quinoline Alkaloids Plants Zanthoxylum gilletii (De Wild.) P.G.Waterman
Target:
Cat. No.: HY-186053
CAS No.: 1220533-66-3
Antimalarial agent 56 is an orally active antimalarial agent. Antimalarial agent 56 inhibits the growth of both drug-sensitive and drug-resistant Plasmodium falciparum strains in vitro. Antimalarial agent 56 can be used in malaria research .
Cat. No.: HY-N18294
CAS No.: 137196-25-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
