26 Results for "

Polypeptide substrate

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Polypeptide substrate" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-B0804
CAS No.: 42200-33-9
Synonyms: SQ-11725
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2). Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research .
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Cat. No.: HY-W007599
CAS No.: 2483-46-7
Target:  

Drug Derivative

Research Areas:  

Cancer

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer for non-viral gene delivery in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid can be used in the preparation of organic substances that enhance the luminescence intensity of alkaline phosphatase substrates .
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Cat. No.: HY-129987
CAS No.: 15087-02-2
Purity:  99.46%
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) sodium is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) sodium regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) sodium induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) sodium can be used in studies related to intrahepatic cholestasis .
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Cat. No.: HY-W353102
CAS No.: 1806-98-0
Estradiol 17-(β-D-Glucuronide) is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) can be used in studies related to intrahepatic cholestasis .
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Cat. No.: HY-P4474
CAS No.: 17011-78-8
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Pz-Pro-Leu-Gly-Pro-d-Arg is a synthetic polypeptide substrate. Pz-Pro-Leu-Gly-Pro-d-Arg can be used to detect the collagenase-like activity of enzymes from various sources, such as Bacillus sp. AH-101 .
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Cat. No.: HY-P5979
CAS No.: 1071466-49-3
Target:  

LRRK2

Research Areas:  

Neurological Disease

LRRKtide is a polypeptide substrate. LRRKtide is a specific phosphorylation substrate of LRRK2, a kinase associated with Parkinson's disease, and its phosphorylation site is a threonine residue. LRRKtide can be used for characterization of the catalytic properties of LRRK2, as well as studies on kinase activity and inhibition. LRRKtide is applicable to research related to Parkinson's disease .
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Cat. No.: HY-P4581
CAS No.: 128802-78-8
Synonyms: Suc-ALPF-pNA
Target:  

FKBP

Research Areas:  

Others

Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a synthetic polypeptide substrate that targets FK506-binding protein (FKBP). Suc-Ala-Leu-Pro-Phe-pNA can be used to determine peptidyl-prolyl cis-trans isomerase activity via the chymotrypsin-coupled assay. Suc-Ala-Leu-Pro-Phe-pNA serves as a substrate for human FK506-binding protein hFKBP-12 in the chymotrypsin-FKBP coupled PPIase assay. Suc-Ala-Leu-Pro-Phe-pNA is applicable for the detection and research of PPIase activity .
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Cat. No.: HY-P4560
CAS No.: 13589-02-1
Synonyms: Pro-Phe
H-Pro-Phe-OH is a dipeptide containing proline and phenylalanine, which can serve as a substrate for prolinase. H-Pro-Phe-OH can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983) .
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Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Target:  

MMP

Research Areas:  

Others

MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
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Cat. No.: HY-P4561
CAS No.: 90331-82-1
Target:  

Cathepsin

Research Areas:  

Others

H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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Cat. No.: HY-P4582
CAS No.: 110906-89-3
Synonyms: Suc-FAAF-pNA
Target:  

Ser/Thr Protease

Research Areas:  

Others

Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a chromogenic polypeptide substrate that can be used for the quantitative activity assay of intracellular subtilisin (ISP) and neutral metalloprotease (NPS) derived from Saccharomonospora canescens. Suc-Phe-Ala-Ala-Phe-pNA is hydrolyzed by the catalytic triad of mature proteases to release the chromophore pNA. Suc-Phe-Ala-Ala-Phe-pNA is applicable to enzymological studies .
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Cat. No.: HY-P4474A
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Pz-Pro-Leu-Gly-Pro-d-Arg TFA is a synthetic polypeptide substrate. Pz-Pro-Leu-Gly-Pro-d-Arg TFA can be used to detect the collagenase-like activity of enzymes from various sources, such as Bacillus sp. AH-101 .
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Cat. No.: HY-P4558
CAS No.: 71227-70-8
Target:  

Dipeptidyl Peptidase

Research Areas:  

Others

H-Pro-Lys-OH is a dipeptide containing proline and lysine, which can serve as a substrate for iminodipeptidase (prolinase). H-Pro-Lys-OH can also be used for the synthesis of polypeptides .
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Cat. No.: HY-P4558A
Target:  

Dipeptidyl Peptidase

Research Areas:  

Others

H-Pro-Lys-OH TFA is a dipeptide containing proline and lysine, which can serve as a substrate for iminodipeptidase (prolinase). H-Pro-Lys-OH TFA can also be used for the synthesis of polypeptides .
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Cat. No.: HY-P4569
CAS No.: 23827-93-2
Target:  

Dipeptidyl Peptidase

Research Areas:  

Others

H-Ser-Pro-OH is a dipeptide containing serine and proline, which can serve as a substrate for prolinase I (PD I) and PD II. H-Ser-Pro-OH can also be used for the synthesis of polypeptide .
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Cat. No.: HY-D2817
Target:  

Fluorescent Dye

Research Areas:  

Others

FITC-PLL is a fluorescently labeled polycationic polypeptide probe composed of polylysine (PLL) and FITC (HY-66019), with a typical Ex/Em of 495/520 nm. The fluorescence intensity and lifetime of FITC-PLL are sensitive to pH and FITC density. FITC-PLL can be used for quantifying hapten receptor binding and endocytosis kinetics in macrophages, as a patternable substrate for neuron guidance, for negatively charged phospholipid membrane binding and transmembrane transport, and for live-cell imaging of starch nanoparticle conjugates and lysosome labeling .
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Cat. No.: HY-B0804R
CAS No.: 42200-33-9
Synonyms: SQ-11725 (Standard)
Nadolol (Standard) is the analytical standard of Nadolol. This product is intended for research and analytical applications. Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2). Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research .
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Cat. No.: HY-P5377
CAS No.: 221055-89-6
Synonyms: Cathepsin K substrate
Target:  

Ser/Thr Protease

Research Areas:  

Others

Abz-HPGGPQ-EDDnp (Cathepsin K substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption. It has potential as a drug target in autoimmune diseases and osteoporosis.This FRET peptide can be used to monitor selectively cathepsin K activity in physiological fluids and cell lysates. Abz-HPGGPQ-EDDnp [where Abz represents o-aminobenzoic acid and EDDnp represents N -(2, 4-dinitrophenyl)-ethylenediamine], a substrate initially developed for trypanosomal enzymes, is efficiently cleaved at the Gly-Gly bond by cathepsin K. This peptide is resistant to hydrolysis by cathepsins B, F, H, L, S and V, Ex/Em=340 nm/420 nm.)
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Cat. No.: HY-P5473
CAS No.: 562082-63-7
Target:  

Inhibitory Antibodies

Research Areas:  

Others

EA2 is a biological active peptide. (This is a peptide substrate for polypeptide N-acetylgalactosaminyltransferase (polypeptide GalNAc-T).)
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Cat. No.: HY-P3745
CAS No.: 65189-70-0
Target:  

PKA

Research Areas:  

Others

H1-7 (histone H1 phosphorylation site), PKA Substrate, a synthetic polypeptide, can be used as PKA substrate .
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