9 Results for "

RGMA

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "RGMA" in MCE Product Catalog:

Cat. No.: HY-P99359
CAS No.: 1791416-49-3
Synonyms: ABT-555; AE12-1Y-QL; Anti-RGMA Reference Antibody (elezanumab)

Target:  

TGF-beta/Smad

Research Areas:  

Metabolic Disease

Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism .
loading...
    loading...
Cat. No.: HY-P99959
CAS No.: 2379805-59-9
Synonyms: MT-3921; rH116A3

Target:  

TGF-β Receptor

Research Areas:  

Neurological Disease

Unasnemab (MT-3921) is a humanised IgG1 monoclonal antibody that binds to repulsive guidance molecule A (RGMa). Unasnemab improves locomotor function and promotes neuroregeneration. Unasnemab exerts ameliorative effects on hippocampal neurogenesis impairment and cognitive decline in db/db mice, Streptozotocin (STZ) (HY-13753)-induced type 1 diabetic and bilateral common carotid artery stenosis (BCAS)-induced mice. Unasnemab can be used for the research of spinal cord injury, diabetes-induced neurological impairments .
loading...
    loading...
Cat. No.: HY-RS11894
Research Areas:  

Others

RGMA Human Pre-designed siRNA Set A contains three designed siRNAs for RGMA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS18785
Research Areas:  

Others

Rgma Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rgma gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS25274
Research Areas:  

Others

Rgma Rat Pre-designed siRNA Set A contains three designed siRNAs for Rgma gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P78508
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: RGMA; RGM
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78197
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: RGMA; RGM
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P76572
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Repulsive guidance molecule A; RGM domain family member A; RGMA; RGM
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P87260
Synonyms: Repulsive guidance molecule A; RGM; RGM domain family member A; RGMA; Repulsive guidance molecule A; RGM; RGM domain family member A

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

loading...
    loading...