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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
RRAS2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "RRAS2" in MCE Product Catalog:
Synonyms: DS11252927
Research Areas:
D927 (DS11252927) is an orally active glucose transporter type 4 (GLUT4) translocation activator with an EC50 of 0.14 μM. D927 enhances the binding affinity of PI3Kα catalytic subunit p110α to canonical RAS proteins (KRAS4A, KRAS4B) and RRAS, RRAS2, MRAS. D927 activates the PI3Kα-AKT pathway (increasing phosphorylation of AKT, p70S6 kinase) without affecting the RAF-ERK1/2 pathway. D927 improves hyperglycemia in type 1 and type 2 diabetes mice model. D927 can be used for the study of glucose homeostasis disorders and diabetes [2].
Cat. No.: HY-W1126235
CAS No.: 2253733-45-6
Synonyms: D223
Target:
Research Areas:
DS02312223 (D223) is a molecular glue that promotes the binding of RAS to PI3Kα, with a Kd of 0.76 μM for p110α. DS02312223 increases the binding affinity between GTP-bound KRAS (KRAS-GMPPNP) and p110α by nearly three orders of magnitude (KD = 0.017 μM). DS02312223 stimulates the translocation of GLUT4 to the plasma membrane. DS02312223 promotes glucose uptake in the absence of insulin. DS02312223 can be used in diabetes research .
Cat. No.: HY-RS12281
Target:
Research Areas:
RRAS2 Human Pre-designed siRNA Set A contains three designed siRNAs for RRAS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22789
Target:
Research Areas:
Rras2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rras2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29303
Target:
Research Areas:
Rras2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rras2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701974
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RRAS2; Ras-related protein R-Ras2; Ras-like protein TC21; Teratocarcinoma oncogene
Cat. No.: HY-P701975
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RRAS2; Ras-related protein R-Ras2; Ras-like protein TC21; Teratocarcinoma oncogene
Cat. No.: HY-P810818
Synonyms: TC21, RRAS2, Ras-related protein R-Ras2, Ras-like protein TC21, Teratocarcinoma oncogene
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
