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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
Retinyl
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "Retinyl" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: Retinol acetate; Vitamin A acetate
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1 Cited Publications
Synonyms: Vitamin A palmitate; Retinol palmitate
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JW480 is a selective KIAA1363/AADACL1 inhibitor with oral activity, featuring IC50 values of 12 nM against human KIAA1363, 20 nM against mouse KIAA1363. JW480 blocks lipid deacetylase activity to restrain HAG metabolism and lowers retinyl ester hydrolase function in hepatic stellate cells. JW480 reduces MAGE lipid levels and inhibits migration, invasion, survival and tumor growth of prostate cancer cells. JW480 lowers PKCδ phosphorylation, facilitates HAGP accumulation, diminishes platelet aggregation, dense granule secretion and Ca 2+ flux, delays arterial thrombosis and prolongs tail bleeding time in rats. JW480 can be used for the study of prostate cancer and thrombosis .
Synonyms: Vitamin A palmitate (Standard); Retinol palmitate (Standard)
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Synonyms: Retinol acetate (Standard); Vitamin A acetate (Standard)
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Cat. No.: HY-N0679S
CAS No.: 118139-36-9
Synonyms: ALK-001; Retinol acetate-d3; Vitamin A acetate-d3
Cat. No.: HY-E70599
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Human CES2 Enzyme is a carboxylesterase involved in drug metabolism and lipid homeostasis. Human CES2 Enzyme hydrolyzes triglycerides, cholesteryl esters and retinyl esters to regulate lipid metabolism and energy homeostasis. Human CES2 Enzyme improves glucose tolerance and insulin sensitivity, reduces hepatic lipid accumulation, alleviates white adipose tissue steatitis, decreases plasma cholesterol levels, and reduces body weight and white adipose tissue weight. Human CES2 Enzyme can be used in the research of metabolic syndrome .
Cat. No.: HY-125859E
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Myeloperoxidase, Human Neutrophil is a peroxidase. Myeloperoxidase, Human Neutrophil is a potent antibacterial agent by catalyzing the H2O2-dependent oxidation of chloride anion to generate hypochlorous acid. Myeloperoxidase, Human Neutrophil catalyzes the degradation of N-retinyl-idene-N-retinylethanolamine, a toxic form of retinal lipofuscin. Myeloperoxidase, Human Neutrophil also triggers lysosomal stress and cell death. Myeloperoxidase, Human Neutrophil can be used for the researches of inflammation and infection .
Cat. No.: HY-A0058
CAS No.: 136778-12-6
Synonyms: Retinyl β-D-glucoside
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Retinyl-β-D-glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.
Cat. No.: HY-N0679S4
CAS No.: 118139-40-5
Synonyms: Retinol acetate-d4; Vitamin A acetate-d4
Cat. No.: HY-N8356A
CAS No.: 34356-29-1
Synonyms: 9-cis-Retinyl palmitate
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Cat. No.: HY-W442049
CAS No.: 893412-73-2
Synonyms: HPR
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Hydroxypinacolone retinoate (HPR) is a retinol derivative, which binds directly with retinoic acid receptors (RARs). Hydroxypinacolone retinoate, when used in combination with Retinyl propionate, can be used in anti-skin aging research .
Cat. No.: HY-177832
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Liposomal Retinyl palmitate is a specialized delivery system that encapsulates retinyl palmitate within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of retinyl palmitate. Retinyl palmitate is a vit
Cat. No.: HY-175663
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EYE-002 is a RPE65 inhibitor with an IC50 of 69 nM. EYE-002 promotes recovery of scotopic ERG a-/b-wave amplitudes. EYE-002 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-002 exerts protective effects against photic retinal damage in mice. EYE-002 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1) .
Cat. No.: HY-175664
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EYE-003 is an orally active RPE65 inhibitor with an IC50 of 102 nM. EYE-003 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-003 suppresses scotopic ERG b-wave amplitude and exerts protective effects against retinal degeneration in Abca4 ⁻/⁻ Rdh8 ⁻/⁻ mice (a STGD1 model) by reducing retinal autofluorescent puncta and preserving outer nuclear layer (ONL) thickness in a dose-dependent manner. EYE-003 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1) .
Cat. No.: HY-145806
CAS No.: 34356-31-5
Synonyms: 13-cis-Retinol acetate; 13-cis-Vitamin A acetate
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Cat. No.: HY-N8356
CAS No.: 26771-20-0
Synonyms: 13-cis-Retinyl palmitate
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Zea mays L. Gramineae Terpenoids Other Diseases Diterpenoids Plants Endogenous metabolite Disease Research Fields
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Cat. No.: HY-W587809
CAS No.: 631-88-9
Synonyms: Retinyl oleate
All-trans-Retinyl oleate (Retinyl oleate) is a synthetic ester formed from the combination of Retinol (vitamin A) and oleic acid. All-trans-Retinyl oleate belongs to the class of retinoids, which are derivatives of vitamin A.
Cat. No.: HY-B1384S
Synonyms: Vitamin A palmitate-d4; Retinol palmitate-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
