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Results for "

S. sclerotiorum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Cytochrome P450 (1) Environmental Pollutants (1) Fungal (24) Isotope-Labeled Compounds (1) Parasite (1) Reference Standards (1) Succinate Dehydrogenase (10)
By Research Areas:	Cancer (2) Infection (25) Inflammation/Immunology (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W021040

Fludioxonil CGA-173506	Environmental Pollutants Fungal Apoptosis	Infection Cancer
Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells .

HY-139983

SDH-IN-1 1 Publications Verification	Fungal	Infection
SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against S. sclerotiorum (EC₅₀ of 0.14 mg/L) .

HY-178799

SDH-IN-37	Succinate Dehydrogenase Fungal	Infection
SDH-IN-37 (Compound A37) is a potent SDH inhibitor, with an IC₅₀ value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC₅₀ values of 0.0144, 0.882 and 1.99 μg/mL, respectively .

HY-W021040R

Fludioxonil (Standard) CGA-173506 (Standard)	Reference Standards Fungal	Infection
Fludioxonil (Standard) is the analytical standard of Fludioxonil. This product is intended for research and analytical applications. Fludioxonil, a phenylpyrrole fungicide, has a strong inhibition on mycelia growth of S. sclerotiorum .

HY-178801

SDH-IN-39	Succinate Dehydrogenase Fungal	Infection
SDH-IN-39 (Compound A16) is a SDH inhibitor, with an IC₅₀ value of 6.83 μg/mL. SDH-IN-39 is also an antifungal agent. SDH-IN-39 shows antifungal activity against Rhizoctonia solani (EC₅₀ of 1.49 μg/mL), G. zeae, C. gloeosporioides, S. sclerotiorum and M. oryzae .

HY-178717

WML-01	Fungal	Infection
WML-01 is a fungicide with *EC₅₀s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi* and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic .

HY-162458

Antifungal agent 100	Fungal	Infection Inflammation/Immunology
Antifungal agent 100 (compound 3i) exhibits significant antifungal effects against S. sclerotiorum with an EC₅₀ value of 0.33 mg/L. Antifungal agent 100 displays an IC₅₀ of 0.63 mg/mL against the Succinate dehydrogenase (SDH) of S. sclerotiorum .

HY-155703

LW3	Fungal	Infection
LW3 is a potent antifungal agent. LW3 has antifungal activity with EC₅₀ values of 0.54, 0.09, 1.52, and 2.65 mg/L against B. cinerea, R. solani, S. sclerotiorum, and F. graminearum, respectively .

HY-162559

SDH-IN-16	Fungal	Infection
SDH-IN-16 (compound 5aa) is a potent inhibitor of Succinate Dehydrogenase, with the IC₅₀ of 1.62 μM. SDH-IN-16 displays a broad spectrum of antifungal activity against F. graminearum, B. cinerea, S. sclerotiorum, and R. solani, with the corresponding EC₅₀ values of 0.12, 4.48, 0.33, and 0.15 μg/mL, respectively .

HY-163890

Succinate dehydrogenase-IN-2	Succinate Dehydrogenase Parasite	Infection
Succinate dehydrogenase-IN-2 (Compound 12x) is an inhibitor for succinate dehydrogenase (SDH) with an IC₅₀ of 1.22 mg/L. Succinate dehydrogenase-IN-2 exhibits antifungal activity, that inhibits S. sclerotiorum, V. mali, G. graminis, R. solani and B. cinerea with EC₅₀ of 0.52-3.42 mg/L .

HY-175501

Succinate dehydrogenase-IN-11	Fungal Succinate Dehydrogenase	Infection
Succinate dehydrogenase-IN-11 (Compound A12) is a succinate dehydrogenase inhibitor with an IC₅₀ value of 3.58 μM. Succinate dehydrogenase-IN-11 exhibits antifungal activity. Succinate dehydrogenase-IN-11 shows activity against fungi such as R. solani, B. cinerea, F. graminearum, and S. sclerotiorum in vitro. Succinate dehydrogenase-IN-11 also exerts a controlling effect on R. solani, P. pachyrhizi, and P. sorghi in vivo. Succinate dehydrogenase-IN-11 can be used in research related to antifungal applications .

HY-161375

SDH-IN-13	Fungal	Infection
SDH-IN-13 (Compound 5IIIh) is a SDH inhibitor (IC₅₀: 13.7 μg/mL) and an antifungal agent .

HY-132912

Antifungal agent 15	Fungal	Infection
Antifungal agent 15 has the most potent activity with EC₅₀ values of 0.52 and 0.50 μg/mL against S. sclerotiorum and B. cinerea, respectively.

HY-178050

SDH-IN-30	Fungal Succinate Dehydrogenase	Infection
SDH-IN-30 (Compound 7m) is a Succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 0.34 μM. SDH-IN-30 has potent antifungal activities against Rhizoctonia solani and Sclerotinia sclerotiorum with EC₅₀ s of 0.004 and 0.028 μg/mL. SDH-IN-30 also has remarkable protective and curative efficacies against R. solani and significantly inhibits S. sclerotiorum growth on oilseed rape leaves by damaging the fungal cell structure. SDH-IN-30 can be used for fungal infections like rice sheath blight (RSB) and sclerotinia stem rot (SSR) research .

HY-163284

SDH-IN-12	Succinate Dehydrogenase Fungal	Infection
SDH-IN-12 (compound 9b) is a succinate dehydrogenase inhibitor, which exhibits activity against S. sclerotiorum and C. arachidicola, with *EC₅₀*s of 0.97 and 2.07 μM, respectively. SDH-IN-12 reveals no significant herbicidal activity against monocotyledonous and dicotyledonous plants .

HY-158054

Antifungal agent 95	Fungal	Infection
Antifungal agent 95 (Compound CN21b) is an antifungal agent for Sclerotinia sclerotiorum and Botrytis cinerea, with *EC₅₀s of 2.11 and 0.97 μM, respectively. Antifungal agent 95 exhibits antifungal activity against resistant B. cinerea* strains, with *EC₅₀*s less than 10 μM .

HY-N8499

Sporothriolide	Fungal	Infection
Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC₅₀ values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo .

HY-179270

CYP51-IN-30	Fungal Cytochrome P450	Infection
CYP51-IN-30 is a CYP51 inhibitor and fungicidal agent. CYP51-IN-30 inhibits CYP51 activity. CYP51-IN-30 displays potent fungicidal activity with an EC₅₀ value of 2.97 mg/L against S. sclerotiorum .

HY-176140

Succinate dehydrogenase-IN-9	Fungal Succinate Dehydrogenase	Infection
Succinate dehydrogenase-IN-9 (Compound Iik) is a succinate dehydrogenase inhibitor (IC₅₀: 3.6 μM). Succinate dehydrogenase-IN-9 exhibits potent inhibitory activity against various fungal species (eg: inhibits S. sclerotiorum with an EC₅₀ value of 1.14 μg/mL. Succinate dehydrogenase-IN-9 enhances the nitrate reductase activity, thereby facilitating plant growth .

HY-W021040S

Fludioxonil-13C3 CGA-173506-¹³C₃	Isotope-Labeled Compounds Fungal Apoptosis	Infection Cancer
Fludioxonil- ¹³C₃ (CGA-173506- ¹³C₃) is ¹³C labeled Fludioxonil. Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells .

HY-174390

SDH-IN-29	Fungal Succinate Dehydrogenase	Infection
SDH-IN-29 (Compound A33) is a SDH inhibitor with an IC₅₀ of 0.0709 μM. SDH-IN-29 has a broad spectrum of antifungal activities (EC₅₀s of 0.356, 0.798 and 0.146 μg/mL for Fusarium graminearum, Sclerotinia sclerotiorum, and Rhizoctonia solani, respectively). SDH-IN-29 has moderate to significant protective effects against rice blast, wheat scab and cucumber powdery mildew .

HY-125511

Chaetoviridin A	Fungal	Infection
Chaetoviridin A exhibits antifungal activity against several plants pathogen, inhibits growth of Verticillium dahliae through cell necrosis and mycelial deformation, and thus improves sensitivity of V. dahliae to stress, increases the emergence rate and plant height of cotton .

HY-178051

Antifungal agent 135	Succinate Dehydrogenase Fungal	Infection
Antifungal agent 135 (Compound C2), an antifungal agent, is a Succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 1.99 μM. Antifungal agent 135 has potent antifungal activities against Valsa mali, Sclerotinia sclerotiorum and Phytophthora capsici with EC₅₀ s of 0.280, 1.11 and 0.130 mg/L, respectively. Antifungal agent 135 shows protective and curative activities against Phytophthora capsici and Valsa mali by effectively disrupting hyphal structural integrity and inhibiting mycelial growth .

HY-179296

SDH-IN-41	Fungal	Infection
SDH-IN-41 (Compound 3d-1) is an antifungal agent, SDH inhibitor, with an IC₅₀ value of 4.14 mg/L against SsSDH. SDH-IN-41 shows antifungal activity against S. sclerotiorum with an EC₅₀ value of 1.86 mg/L .

HY-183722

SDH-IN-46	Fungal Succinate Dehydrogenase	Infection
SDH-IN-46 is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 1.21 μM. SDH-IN-46 disrupts fungal respiration via mitochondrial respiratory chain enzyme targeting and exhibits broad-spectrum antifungal activity. SDH-IN-46 exhibits substantial protective effects against S. sclerotiorum on oilseed rape leaves, Rhizoctonia solani on rice leaves, and Valsa mali on apple fruits .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8499

Sporothriolide	Natural Products Microorganisms Source Classification	Fungal
Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC₅₀ values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo .

HY-125511

Chaetoviridin A	Natural Products Microorganisms Source Classification	Fungal
Chaetoviridin A exhibits antifungal activity against several plants pathogen, inhibits growth of Verticillium dahliae through cell necrosis and mycelial deformation, and thus improves sensitivity of V. dahliae to stress, increases the emergence rate and plant height of cotton .

Cat. No.	Product Name	Chemical Structure

HY-W021040S

Fludioxonil-13C3
Fludioxonil- ¹³C₃ (CGA-173506- ¹³C₃) is ¹³C labeled Fludioxonil. Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells .

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S. sclerotiorum

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products