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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
SEB
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "SEB" in MCE Product Catalog:
16
16 Cited Publications
Cat. No.: HY-19744
CAS No.: 2437475-16-4
Target:
Research Areas:
T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC50s of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively .
3
3 Cited Publications
Cat. No.: HY-P71808
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: entBEnterotoxin type B; SEB
Species:
Source:
Research Areas:
Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor. Z-Asp-CH2-DCB also inhibits proteases with caspase-like activity. Z-D-CH2-DCB blocks the production of IL-1β, TNF-α, IL-6, and IFN-γ in staphylococcal enterotoxin B (SEB)-stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB-1-stimulated T-cell proliferation in a dose-dependent manner. Z-Asp-CH2-DCB prevents SU5416-induced septal cell apoptosis and emphysema development .
Cat. No.: HY-163035
CAS No.: 1206480-93-4
Target:
Research Areas:
EM-163 is a summative BB-Loop analog. EM-163 can alleviate inflammation and prevent death from toxic shock by targeting the TIR domain of MyD88. EM-163 can be used in the study of SEB poisoning (SEB: Staphylococcal enterotoxin B) .
Cat. No.: HY-W040216
CAS No.: 85261-19-4
Synonyms: N-Nonanoyl-N-methylglucamine
Cat. No.: HY-121053
CAS No.: 127266-56-2
Synonyms: WY-50324; SEB-324
Target:
Research Areas:
Adatanserin (WY-50324) is a high affinity, selective and partial agonist for the 5-HT1A receptor with a Ki of 1 nM. Adatanserin is a moderate affinity 5-HT2 receptor antagonist with a Ki of 73 nM. Adatanserin shows significant anxiolytic and antidepressant activity in an animal conflict model .
Cat. No.: HY-121053A
CAS No.: 144966-96-1
Synonyms: WY-50324 hydrochloride; SEB-324 hydrochloride
Target:
Research Areas:
Adatanserin hydrochloride is a high affinity, selective and partial agonist for the 5-HT1A receptor with a Ki of 1 nM. Adatanserin hydrochloride is a moderate affinity 5-HT2 receptor antagonist with a Ki of 73 nM. Adatanserin hydrochloride shows significant anxiolytic and antidepressant activity in an animal conflict model .
Cat. No.: HY-RS12739
Target:
Research Areas:
SETBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SETBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21929
Target:
Research Areas:
Setbp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Setbp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703336
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RNPC1; SEB4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
