10 Results for "

SHH pathway

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "SHH pathway" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B0508
CAS No.: 16773-42-5
Synonyms: Ro 7-0207
Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
loading...
    loading...
Cat. No.: HY-108439
CAS No.: 937807-66-4
Purity:  ≥99.0%
Target:  

Wnt Hedgehog

Research Areas:  

Neurological Disease

Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. .
loading...
    loading...
Cat. No.: HY-P10875
CAS No.: 2130846-15-8
Target:  

Hedgehog

Research Areas:  

Cancer

HL2-m5 is the inhibitor for the interaction between sonic hedgehog/patched (Shh/PTCH1) with Kd of 170 nM for Shh. HL2-m5 inhibits activation of Hedgehog signaling pathway and transcription of Gli-controlled gene with an IC50 of 230 nM .
loading...
    loading...
Cat. No.: HY-B0508S1
Synonyms: Ro 7-0207-13C2,15N2
Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
loading...
    loading...
Cat. No.: HY-116455
CAS No.: 1446352-30-2
Target:  

Fluorescent Dye

Research Areas:  

Cancer

BRD-9526 is a potent and selective Sonic Hedgehog (Shh) pathway inhibitor with potential anti-cancer activity. The mechanism of BRD-9526 is similar in some ways to commonly used inhibitors such as cyclopamine, but is significantly different in other ways. The discovery of BRD-9526 may provide a useful probe for studying complex signaling pathways .
loading...
    loading...
Cat. No.: HY-B0508S
CAS No.: 2747915-64-4
Synonyms: Ro 7-0207-d5
Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
loading...
    loading...
Cat. No.: HY-B0508R
CAS No.: 16773-42-5
Synonyms: Ro 7-0207 (Standard)
Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
loading...
    loading...
Cat. No.: HY-108439R
CAS No.: 937807-66-4
Research Areas:  

Neurological Disease

Neurodazine (Standard) is the analytical standard of Neurodazine (HY-108439). This product is intended for research and analytical applications. Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. .
loading...
    loading...
Cat. No.: HY-FLB0508
CAS No.: 16773-42-5
Synonyms: Ro 7-0207 solution
Research Areas:  

Infection Cancer

Ornidazole solution is mainly composed of Ornidazole (HY-B0508). Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
loading...
    loading...
Cat. No.: HY-W338819
CAS No.: 25122-41-2
Clobetasol is a glucocorticoid and Smoothened agonist that can cross the blood-brain barrier. Clobetasol induces Smo-dependent activation of the Shh signaling pathway and nuclear translocation of Gli1. Clobetasol promotes remyelination and reduces myelin loss in lesions of neuromyelitis optica (NMO). Clobetasol may cause adrenal suppression, cushingoid appearance, and local adverse reactions including dysgeusia, xerostomia, and gastroesophageal burning. Clobetasol can be used in research related to neurodegenerative diseases, oral lichen planus, mucous membrane pemphigoid, and neuromyelitis optica .
loading...
    loading...