Ornidazole solution
Ornidazole solution is mainly composed of Ornidazole (HY-B0508). Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.
For research use only. We do not sell to patients.
- CAS No.: 16773-42-5
- Formula: C7H10ClN3O3
- Molecular Weight:219.63
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
-
CAS No. 16773-42-5
-
Molecular Weight 219.63
-
Formula C7H10ClN3O3
-
SMILES
CC1=NC=C(N1CC(O)CCl)[N+]([O-])=O
-
Synonyms
Ro 7-0207 solution
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128(4): p. 856-61. [Content Brief]
[2]. Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14(4): p. 609-13. [Content Brief]
[3]. Evyapan G, et al., Ornidazole suppresses CD133+ melanoma stem cells via inhibiting hedgehog signaling pathway and inducing multiple death pathways in a mouse model. Croat Med J. 2022 Oct 31;63(5):461-474. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)