8 Results for "

SMS 2

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "SMS 2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N8518
CAS No.: 63335-25-1
Malabaricone C is an orally active and noncompetitive sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells .
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3
3 Cited Publications
Cat. No.: HY-114307
CAS No.: 1883528-69-5
Purity:  99.85%
Target:  

Phospholipase

Research Areas:  

Inflammation/Immunology

Ly93 is a selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with an IC50 of 91 nM .
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3
3 Cited Publications
Cat. No.: HY-102041
CAS No.: 2098890-15-2
Purity:  98.04%
Target:  

Phospholipase

Research Areas:  

Inflammation/Immunology

SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM) .
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Cat. No.: HY-112713
CAS No.: 2241838-28-6
Purity:  ≥98.0%
Target:  

Phospholipase

Research Areas:  

Inflammation/Immunology

SMS2-IN-2 is a potent, highly selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM and 56 μM for SMS2 and SMS1, respectively. Anti-chronic inflammatory activity .
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Cat. No.: HY-150559
CAS No.: 2414240-89-2
Target:  

Phospholipase

Research Areas:  

Infection Others Cancer

SMS2-IN-3 is a potent and selective SMS2inhibitor (IC50=2.2 nM), significantly reduces the hepatic SM (22:0) levels .
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Cat. No.: HY-102041R
CAS No.: 2098890-15-2
SMS2-IN-1 (Standard) is the analytical standard of SMS2-IN-1 (HY-102041). This product is intended for research and analytical applications. SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM) .
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Cat. No.: HY-N8518R
CAS No.: 63335-25-1
Malabaricone C is an orally active and noncompetitive sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells .
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Cat. No.: HY-P73632
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Phosphatidylcholine:ceramide cholinephosphotransferase 2; Sphingomyelin synthase 2; SGMS2; SMS2
Species:  
Source:  
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