2098890-15-2
Chemical Structure
SMS2-IN-1
- CAS No.: 2098890-15-2
- Formula:C34H37F6N3O5
- Molecular Weight:681.67
IUPAC Name: 1-methylcyclopropyl 4-(3-((3-((3,5-bis(trifluoromethyl)benzyl)(methyl)carbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy)propyl)piperidine-1-carboxylate
InChIKey: JDQOICVJUDEXEQ-UHFFFAOYSA-N
SMILES: O=C1C(C(N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C)=O)=C(OCCCC3CCN(C(OC4(CC4)C)=O)CC3)C5=CC=CC=C5N1C
Biological Activity: SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SMS2-IN-1 | 98.00% | SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM). | ||||||||||||||||||||
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SMS2-IN-1 (Standard) | ≥98% | SMS2-IN-1 (Standard) is the analytical standard of SMS2-IN-1 (HY-102041). This product is intended for research and analytical applications. SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM). | ||||||||||||||||||||
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-
Similarity Score 0.77
HY-150559SMS2-IN-3 -
Similarity Score 0.49
HY-179321PROTAC HDAC4 Degrader-1 -
Similarity Score 0.48
HY-156570DGKα-IN-3 -
Similarity Score 0.47
HY-10528RTasquinimod (Standard) -
Similarity Score 0.47
HY-156569DGKα-IN-2 -
Similarity Score 0.47
HY-146034NOD1/2 antagonist-1 -
Similarity Score 0.46
HY-10528STasquinimod-d3 -
Similarity Score 0.46
HY-167679Scio-323 -
Similarity Score 0.45
HY-18006NKP608 -
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