DGKα-IN-3
DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
For research use only. We do not sell to patients.
- CAS No.: 2648418-86-2
- Formula: C26H27F3N4O3
- Molecular Weight:500.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
283 nM (DGKα)
Chemical Information
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CAS No. 2648418-86-2
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Molecular Weight 500.51
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Formula C26H27F3N4O3
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SMILES
O=C(C1=C(N2CCC3(CC2)CN(CC3)C4=CC=C(C=C4)OC(F)(F)F)C5=C(C=CC=C5)N(C)C1=O)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)