DGKα-IN-3
DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
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- CAS. Nr.: 2648418-86-2
- Formel: C26H27F3N4O3
- Molecular Weight:500.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
283 nM (DGKα)
Chemical Information
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CAS. Nr. 2648418-86-2
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Molecular Weight 500.51
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Formel C26H27F3N4O3
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SMILES
O=C(C1=C(N2CCC3(CC2)CN(CC3)C4=CC=C(C=C4)OC(F)(F)F)C5=C(C=CC=C5)N(C)C1=O)N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DGKα-IN-3 Related Classifications
HY-156570 Related Classifications
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