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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
SOS response
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "SOS response" in MCE Product Catalog:
Cat. No.: HY-U00035
CAS No.: 1000277-08-6
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Research Areas:
MGB-BP-3 is an orally aective Gram-positive bactericide and DNA-binding agent. MGB-BP-3 blocks transcription initiation by binding to AT-rich bacterial DNA regions, and interferes with the functions of DNA gyrase and topoisomerase IV, but does not stabilize cleavage complexes or induce the SOS response. MGB-BP-3 induces energy depletion in *Staphylococcus aureus* and inhibits spore formation in *Clostridioides difficile*, exhibiting intrinsic resistance resilience. MGB-BP-3 can be used in the research of *Clostridioides difficile*-associated diseases .
Cat. No.: HY-172976
CAS No.: 929202-79-9
Antibacterial agent 279 (compound A12) is a potent antibacterial agent. Antibacterial agent 279 inhibits Pseudomonas aeruginosa SOS response .
Cat. No.: HY-N9110
CAS No.: 70987-96-1
Category:
Flavonoids Monophenols Entada phaseoloides (L.) Merr. Flavones Labiatae Other Diseases Phenols Plants Disease Research Fields
Target:
Cat. No.: HY-114748
CAS No.: 216774-38-8
AHU1 is a compound that inhibits the expression of Shiga toxin type 2 in Escherichia coli O157:H7, demonstrating a dose-dependent reduction in toxin activity by interfering with the SOS response through its effects on RecA.
Cat. No.: HY-126258
CAS No.: 1458674-25-3
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Research Areas:
IMP-1700 is a potent DNA damage potentiator and antibacterial agent. IMP-1700 inhibits the bacterial SOS response to DNA damage. IMP-1700 potently sensitizes MRSA to Ciprofloxacin (HY-B0356) with an EC50 of 5.9 nM. IMP-1700 inhibits the growth of E. coli K-12 BW25113, S. aureus SH1000 and MRSA USA300 JE2 .
Cat. No.: HY-183242
CAS No.: 120154-96-3
Research Areas:
Eilatin is a seven-ring pyridoacridine marine alkaloid with anticancer, antibacterial, and antiparasitic activities. Eilatin acts as a DNA intercalator with selectivity for electron-deficient polycyclic purines; it can chelate Ni 2+ ions and cleave DNA via hydroxyl radical generation. Eilatin induces the SOS response in bacteria, inhibits cancer cell proliferation, and induces cancer cell differentiation and reversion of transformation. The IC50 of Eilatin against Trypanosoma brucei brucei is 1.33 μM. Eilatin can be used in research related to colon tumors, neuroblastoma, chronic myeloid leukemia, acute myeloid leukemia, and trypanosome infections .
Cat. No.: HY-W077245
CAS No.: 16079-88-2
Synonyms: BCDMH
Bromochloro-5,5-dimethylhydantoin (BCDMH) is a fungicide. Bromochloro-5,5-dimethylhydantoin disrupts bacterial cell membranes, alters membrane structure and permeability, and induces leakage of soluble proteins and ions. Bromochloro-5,5-dimethylhydantoin is applicable to studies related to bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
